[Takayasu Mikuni] Comprehensive, single-cell analysis of the localization and dynamics of endogenous proteins in brain tissue

Research Director

Takayasu Mikuni

Takayasu Mikuni

Neuronal Signal Transduction Group, Max Planck Florida Institute for Neuroscience
Research Fellow
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Outline

One of the most dense and complicated tissues, brain tissue contains thousands of proteins that play roles in various brain functions. I will develop a method that allows for the labeling of any endogenous protein with any tag within single brain cells via genome editing, thereby enabling high-throughput imaging of protein localization and dynamics in brain tissue with high specificity, sensitivity, resolution and contrast. This method will provide a new platform to comprehensive understanding of brain functions at the cellular and molecular level.

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