Kuroda Team　　Result

(24)2010 Honda, M., Urakubo, H., Tanaka, K. and Kuroda, S., “Analysis of development of direction selectivity in retinotectum by a neural circuit model with Spike Timing Dependent Plasticity.”, The Journal of Neuroscience, 2011 Jan.26 31(4) 1516-27.

(23)2010　Otsuji, M., Terashima, Y., Ishihara, S., Kuroda, S. and Matsushima, K., “A Conceptual Molecular Network for Chemotactic Behaviors Characterized by Feedback of Molecules Cycling Between the Membrance and the Cytosol.”, Science Signaling,3(152),ra89,2010(DOI:10.1126)

(22)2010 Fujita, K., Toyoshima, Y., Uda, S., Ozaki, Y., Kubota, H. and Kuroda, S., “Decoupling of Receptor and Downstream Signals in the Akt Pathway by Its Low-Pass Filter Characteristics.” ,Science Signaling,3(132),ra56,2010(DOI: 10.1126)

(21)2010 Ozaki Y, Uda S, Saito TH,Chung J, Kubota H, and Kuroda S. A quantitative image cytometry technique for time series or population analyses of signaling networks. PLoS ONE,Apr.1;5(4):e9955, 2010.

(20)2010　 Chung J, Kubota H, Ozaki Y, Uda S, and Kuroda S.　Timing-dependent actions of NGF required for cell differentiation.PLoS ONE,,Feb.2;5(2).e9011, 2010

(19)2009 Takashima M, Ogawa W, Hayashi K, Inoue H, Kinoshita S, Okamoto Y, Sakaue H, Wataoka Y, Emi A, Senga Y, Matsuki Y, Watanabe E, Hiramatsu R, KasugaM. Role of KLF15 in regulation of hepatic gluconeogenesis and metformin action. Diabetes,Jul;59(7),1608-15.2010

(18)2009 Nakamichi S, Senga Y, Inoue H, Emi A, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M. Role of the E3 ubiquitin ligase GRAIL in glucose and lipid metabolism in the liver. J Mol Endocrinol. 42(2):161-169, 2009

(17)2009 Nagare T, Sakaue H, Takashima M, Takahashi K, Gomi H, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M. The Kruppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes. Biochem Biophys Res Commun. 379(1):98-103, 2009

(16)2009　 Yoshioka T, Inagaki K, Noguchi T, Sakai M, Ogawa W, Hosooka T, Iguchi H, Watanabe E, Matsuki Y, Hiramatsu R, Kasuga M. Identification and characterization of an alternative promoter of the human PGC-1alpha gene. Biochem Biophys Res Commun. 381(4):537-543, 2009

(15)2009 Park SG, Schulze-Luehrman J, Hayden MS, Hashimoto N, Ogawa W, Kasuga M, Ghosh S. The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells. Nat Immunol. 10(2):158-66, 2009

(14)2009　．Ito K, Akazawa H, Tamagawa M, Furukawa K, Ogawa W, Yasuda N, Kudo Y, Liao CH, Yamamoto R, Sato T, Molkentin JD, Kasuga M, Noda T, Nakaya H, Komuro I. PDK1 coordinates survival pathways and beta-adrenergic response in the heart. Proc Natl Acad Sci U S A. 106(21):8689-8694,(2009)

(13) Nov.9 2008 Wataru Ogawa.: Regulation of hepatic energy metabolism by insulin. 13th International Congress of Endocrinology. Rio ｄe Janeiro, Brazil.

(12) Apr. 2008 ：“NIBB-EMBL-CRG Workshop on Systems Biology” Temporal coding of ERK signaling network, Barcelona April 2008

(11) 2008 Ogawa W, Kasuga M: Fat stress and liver resistance. Science. 322:1483-1484, 2008

(10) 2008 Yu-ichi Ozaki, Shinsuke Uda, and Shinya Kuroda Specific features of transient Ras and sustained Rap1 activation Book: Systems Biology: the Challenge of Complexity

(9) Dec.5 2008 Nakamichi S, Senga Y, Inoue H, Emi A, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M. Role of the E3 ubiquitin ligase GRAIL in glucose and lipid metabolism in the liver. J Mol Endocrinol. 2008 Dec 5.

(8) Dec.16 2008 Nagare T, Sakaue H, Takashima M, Takahashi K, Gomi H, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M. The Kruppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes.Biochem Biophys Res Commun. 2008 Dec 16.

(7) 2008 Nakamura K, Sakaue H, Nishizawa A, Matsuki Y, Gomi H, Watanabe E, Hiramatsua R, Tamamori-Adachi M, Kitajima S, Noda T, Ogawa W, Kasuga M. PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression.J Biol Chem. 283:17702-17711, 2008

(6) Feb. 2008 Hidetoshi Urakubo, Minoru Honda, Robert C. Froemke, and Shinya Kuroda:"Requirement of an allosteric kinetics of NMDA receptors for spike-timing-dependent plasticity" Journal of Neuroscience ,in press

(5) 2007 Okamoto Y, Ogawa W, Nishizawa A, Inoue H, Teshigawara K, Kinoshita S, Matsuki Y, Watanabe E, Hiramatsu R, Sakaue H, Noda T, Kasuga M. Restoration of glucokinase expression in the liver normalizes postprandial glucose disposal in mice with hepatic deficiency of PDK1. Diabetes. 2007 56:1000-1009.

(4) Feb.6 2008 Oral presentation:　"Temporal coding of ERK signaling networks" at the FCSB 2008 - International Workshop on Future Challenges for Systems Biology(Tokyo).

(3) Dec.11 2007 Shinya Kuroda gave the invitation lecture on BMB2007 "ERK pathway on Systems Biology ".

(2) May 15 2007 Shinya Kuroda gave the invitation lecture on 2007 EPA International Science Forum on Computational Toxicology"Temporal coding of ERK signaling network"in Durham, NC, USA.

(1) March 18-22.2007Shinya Kuroda,Yu-ichi Ozaki and Kazuhiro Fujita gave the invitation lecture on "EMBO/FEBS/ISF workshop on systems dynamics of intracellular communication"in Jerusalem, Israel.