[Yukiko Gotoh] Homeostatic Regulation and Dysregulation of Neural Stem Cells under Physiological and Pathological Challenges


Research Director

Yukiko Gotoh

Yukiko Gotoh, Ph.D.

The University of Tokyo
Professor
website


Outline

Accumulating evidence indicates that newborn neurons in the adult brain contribute to various cognitive functions as well as stress responses. We have identified an embryonic “origin” cell population that later become adult neural stem cells. In this project, we aim to elucidate the mechanisms by which these “origin” cells are established during embryonic development and maintained until the adult stage, and how stress and other insults may perturb these processes. This study may provide a clue to understanding mental disorders and their therapeutic development.


Yukiko Gotoh_project_figure

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