渡邉 力也(ワタナベ リキヤ)

渡邉 力也
学位
工学博士
所属・職位
東京大学大学院工学系研究科
講師
URL
http://www.nojilab.t.u-tokyo.ac.jp
研究分野
1分子生物物理、微細加工学

原著論文

  1. Soga N, Watanabe R, Noji H. Attolitre-sized lipid bilayer chamber array for rapid detection of single transporters. Sci Rep. 2015 Jun 8;5:11025. doi: 10.1038/srep11025
  2. Watanabe R, Koyasu K, You H, Tanigawara M, Noji H. Torque transmission mechanism via DELSEED loop of F1-ATPase. Biophys J. 2015 Mar 10;108(5):1144-52. doi: 10.1016/j.bpj.2015.01.017
  3. Yukawa A, Watanabe R, Noji H.,Effects of an ATP analogue, adenosine 5'-[α-thio]-triphosphate, on F1-ATPase rotary catalysis, torque generation, and inhibited intermediated formation.Biochem Biophys Res Commun. 2015 Feb 12
  4. Yukawa A, Iino R, Watanabe R, Hayashi S, Noji H.,Key Chemical Factors of Arginine Finger Catalysis of F1-ATPase Clarified by an Unnatural Amino Acid Mutation.Biochemistry. 2015 Jan 20;54(2):472-80
  5. Watanabe R, Soga N, Yamanaka T, Noji H.,High-throughput formation of lipid bilayer membrane arrays with an asymmetric lipid composition.Sci Rep. 2014 Nov 17;4:7076
  6. Watanabe R, Soga N, Fujita D, Tabata KV, Yamauchi L, Hyeon Kim S, Asanuma D, Kamiya M, Urano Y, Suga H, Noji H.,Arrayed Lipid Bilayer Chambers Allow Single-Molecule Analysis of Membrane.Transporter Activity. Nat Commun. 2014 Jul 24;5:4519.
  7. Arai HC, Yukawa A, Iwatate RJ, Kamiya M, Watanabe R, Urano Y, Noji H.,Torque generation mechanism of F1-ATPase upon NTP binding. Biophys J. 2014 Jul 1;107(1):156-64
  8. Watanabe R, Matsukage Y, Yukawa A, Tabata KV, Noji H.,Robustness of the Rotary Catalysis Mechanism of F1-ATPase.J Biol Chem. 2014 Jul 11;289(28):19331-40
  9. Watanabe R, Noji H.,Characterization of the temperature-sensitive reaction of F1-ATPase by using single molecule manipulation.Sci Rep. 2014 May 14;4:4962
  10. Watanabe R, Noji H.,Timing of inorganic phosphate release modulates the catalytic activity of ATP-driven rotary motor protein.Nat Commun. 2014 Apr 1;5:3486
  11. Watanabe, R., Hayashi, K., Ueno, H., & Noji, H. “Catalysis-enhancement via rotary fluctuation of F1-ATPase” Biophys J. 2013 Nov 19;105(10):2385-91. doi: 10.1016/j.bpj.2013.09.050
  12. Watanabe, R., Tabata, KV., Iino, R., Ueno, H., Iwamoto, M., Oiki, S., & Noji, H “Biased Brownian stepping rotation of FoF1-ATP synthase driven by proton motive force” Nature Communications (2013) 4, 1631
  13. Tanigawara, M., Tabata, KV., Ito, Y., Ito, J., Watanabe, R., Ueno, H., Ikeguchi, M., & Noji, H. “Role of the DELSEED Loop in Torque Transmission of F1-ATPase” Biophys J. (2012) 103, 970-8
  14. You, H., Iino, R., Watanabe, R., & Noji, H. “Winding single-molecule double-stranded DNA on a nanometer-sized reel” Nucleic Acids Research (2012) [E-pub]
  15. Watanabe, R., Okuno, D. Sakakihara, S. Shimabukuro, K. Iino, R. Yoshida, M. & Noji, H. “Mechanical modulation of catalytic power on F1-ATPase” Nature Chem Biol (2012) 1, 86-92.
  16. Watanabe, R., Iino, R. & Noji, H. “Phosphate release in F1-ATPase catalytic cycle follows ADP release.” Nature Chem Biol (2010) 6, 814-20.
  17. Enoki, S., Watanabe, R., Iino, R. & Noji, H. “Single-molecule study on the temperature-sensitive reaction of F1-ATPase with a hybrid F1 carrying a single ・(E190D).” J Biol Chem (2009) 284, 23169-76.
  18. Watanabe, R., Iino, R., Shimabukuro, K., Yoshida, M. & Noji, H. “Temperature-sensitive reaction intermediate of F1-ATPase.” EMBO Rep (2008) 9, 84-90.

総説

  1. 渡邉力也. 「FoF1-ATP合成酵素のプロトン駆動力による回転運動の直接観察」 生物物理 (2013) 4, 214-215
  2. Watanabe, R. “Rotary catalysis of FoF1-ATP synthase” Biophysics 9, 51-56 (2013)
  3. Watanabe, R., & Noji, H. “Chemomechanical coupling mechanism of F1-ATPase: Catalysis and torque generation” FEBS Letter (2013) 8, 1030-1035
  4. Watanabe, R., & Noji, H. “Chemomechanical coupling of F1-ATPase under hydrolysis condition” Biophysics (2012) 8, 73-78
  5. 渡邉力也, 野地博行. 「F1の化学反応スキームに関する新しい理解」生物物理(2012) 1, 14-17
  6. 渡邉力也, 野地博行. 「F1-ATPaseにおける回転の角度に依存した触媒活性の制御機構」 ライフサイエンス新着論文レビュー 2011年12月12日
  7. 渡邉力也, 野地博行. 「1分子操作技術に立脚した回転モータータンパク質F1-ATPaseの化学-力学共役機構の解明」 ライフサイエンス新着論文レビュー 2010年10月26日