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JST Press Release

July 03, 2014
Japan Science and Technology Agency (JST)
5-3, Yonbancho, Chiyoda-ku, Tokyo 102-8666

A Novel Cobalt Catalyst Produced Useful Building Blocks with Water as a Sole Side Adduct
– Environmentally Benign and Low-Costing Medicine Synthesis –

They found that a cobalt catalyst promotes dehydrative direct functionalization of carbon-hydrogen bond in organic molecules with allylic alcohols, leading to short, low-costing, and environmentally-friendly synthesis of medicines.

Researcher Information

JST ACT-C (Advanced Catalytic Transformation Program for Carbon Utilization)
Research Area “Creation of Advanced Catalytic Transformation for the Sustainable Manufacturing at Low Energy, Low Environmental Load”
Research Theme “Development and Applications of Cooperative Catalysts towards Life Innovation”

Journal Information

Yudai Suzuki, Bo Sun, Ken Sakata, Tatsuhiko Yoshino, Shigeki Matsunaga, and Motomu Kanai. “Dehydrative Direct C-H Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis”. Angewadnte Chemie International Edition, 2015, Early View, doi: 10.1002/anie.201503704.


[About Research]
Shigeki Matsunaga Ph.D.
Professor, Laboratory of Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University
URL: http://www.pharm.hokudai.ac.jp/yakuzou/index_e.html

[About Program]
Hisao Mizuta
Department of Research Project, JST


JST, an integrated organization of science and technology in Japan, establishes an infrastructure for the entire process from the creation of knowledge to the return to the society. For more information, visit http://www.jst.go.jp/EN/