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JST Press Release

25th January 2013
Japan Science and Technology Agency (JST)
5-3, Yonbancho, Chiyoda-ku, Tokyo 102-8666
URL http://www.jst.go.jp/EN/index.html

Identification of a novel mechanism that facilitates memory in response to hunger

The memory improvement is essential to increase QOL in people suffering from memory impairment. The authors revealed that hunger facilitates memory, and the underlying molecular mechanism using the fruit fly, Drosophila. This work may contribute the memory improvement in the future study.

Researcher Information

JST PRESTO Research Area “Epigenetic control and biological functions”
Research Theme : “Study of epigenetics acting as a memory tag”

Journal Information

Published on 25 January 2013 in “Science”.
Yukinori Hirano, Tomoko Masuda, Shintaro Naganos, Motomi Matsuno, Kohei Ueno, Tomoyuki Miyashita, Junjiro Horiuchi, Minoru Saitoe
“Fasting Launches CRTC to Facilitate Long-Term Memory Formation in Drosophila”
doi: 10.1126/science.1227170


[About Research]
Yukinori Hirano, Ph.D.
Researcher, Tokyo Metropolitan Institute for Neuroscience,

[About Program]
Life Science Group, Department of Innovation Research,
Japan Science and Technology Agency
Shigeru Ishimasa,


JST, an integrated organization of science and technology in Japan, establishes an infrastructure for the entire process from the creation of knowledge to the return to the society. For more information, visit http://www.jst.go.jp/EN/