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小椋 俊彦

蛋白質電顕画像を用いた自動 in silico 擬似結晶構造解析法の開発
研究者紹介
著者・発表者 表題 発表先
Ogura, T., Tong, K.I., Mio, K., Maruyama, Y., Kurokawa, H., Sato, C., Yamamoto, M. Keap1 is a forked-stem dimmer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains Proc. Natl. Acad. Sci USA, Vol.107, pp.2842-2847 (2010)
Ogura, T. Direct observation of unstained wet biological samples by scanning-electron generation X-ray microscopy Biochem. Biophys. Res. Commun., Vol.391, pp.198-202 (2010)
Ogura, T. High-resolution X-ray observation of unstained samples by a newly developed SGXM Nanotechnology, pp.295501 (2010)
K. Mio, T. Ogura, T. Yamamoto, Y. Hiroaki, Y. Fujiyoshi, Y. Kubo, C. Sato, Reconstruction of the P2X2 receptor reveals a vase-shaped structure with lateral tunnels above the membrane Structure, 17, p 266-275 (2009)
Toshihiko Ogura Analyzing indirect secondary electron contrast of unstained bacteriophage T4 based on SEM images and Monte Carlo simulations Biochemical and Biophysical Research Communications 380 (2009) 254-259 (2009/3)
A. Omura, T. Matsuzaki,
K. Mio, T. Ogura,
M. Yamamoto, A. Fujita,
K. Okawa, H. Kitayama,
C. Takahashi, C. Sato,
M. Noda
RECK forms cowbell-shape dimer and inhibits MMP-7-catalyzed cleavage of fibronectin Journal of Biological Chemistry (2009) Vol.284, p3461-3469 (2009/2)
K. Mio, T. Ogura, M. Mio,
H. Shimizu, T.-C. Hwang,
C. Sato, Y. Sohma
Three-dimensional Reconstruction of Human Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel Revealed an Ellipsoidal Structure with Orifices beneath the Putative Transmembrane Domain Journal of Biological Chemistry (2008) Vol.283, No44, p30300-30310 (2008/10/31)
Toshihiko Ogura A high contrast method of unstained biological samples under a thin carbon film by scanning electron microscopy Biochemical and Biophysical Research Communications (2008) Vol.377, p79-84 (2008/12/5)
K. Mio, Y. Kubo, T. Ogura,
T. Yamamoto, F. Arisaka,
C. Sato
The motor protein prestin is a bullet-shaped molecule with inner cavities Journal of Biological Chemistry (2008)
Vol.283, p1137-1145 (2008/1/11)
Y. Maruyama, T. Ogura,
K. Mio, S. Kiyonaka, K. Kato, Y. Mori, C. Sato
Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, Bell shaped structure of transient receptor potential melastatin type2 cation channel Journal of Biological Chemistry (2007)
Vol.282, p36961-36970 (2007/12/27)
M. Yazawa, C. Ferrante, J. Feng, K. Mio,T. Ogura, M. Zhang, P.-H. Lin, Z. Pan, S. Komazaki, K. Kato, M. Nishi, X. Zhao, N. Weisleder, C. Sato, J. Ma, H. Takeshima TRIC channels are essential for Ca2+ handling in intracellular stores Nature (2007) Vol.448, p78-82
小椋 俊彦 電子顕微鏡画像を用いたタンパク質の自動3次元構造解析技術の開発 第六回産学官連携推進会議 (2007/6/16-17)
K.Mio, T.Ogura, S.Kiyonaka, Y.Hiroak, Y.Tanimura, Y.Fujiyoshi, Y.Mori, C.Sato The TRPC3 channel has a large internal chamber surrounded by signal sensing antennas Journal of Molecular Biology (2007) Vol.367, p373-383
T.Ogura, C.Sato A fully automatic 3D reconstruction method using simulated annealing enables accurate posterioric angular assignment of protein projections Journal of Structural Biology, 156(2006) 371-386
T.Ogura, K.Mio,I.Hayashi, H.Miyashita, R.Fukuda,R.Kopan, T.Kodama, T.Hamakubo, T.Iwatsubo, T.Tomita, C.Sato Three-dimensional structure of the γ-secretase complex Biochemical and Biophysical Research Communications 343 (2006) 525-534 (2006/5/5)
K.Mio,Y.Kubo, T.Ogura, T.Yamamoto, C.Sato Visualization of trimetric P2X2 receptor with crown capped extracellular domain Biochemical and Biophysical Research Communications, 337(2005),998-1005
三輪和弘、小椋俊彦、
佐藤主税
イオンチャンネル・受容体の単粒子構造解析 細胞工学、2006、Vol.25,No.3,p236-241
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