 |
| Authors |
Inoue M, Ma L, Aoki J, Ueda H |
| Title |
Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA, an initiator of neuropathic pain |
| Publication |
J. Neurochem., vol. 107, 1556-1565 (2008) |
| Authors |
Ohuchi H, Hamada A, Matsuda H, Takagi A, Tanaka M, Aoki J, Arai H, Noji S |
| Title |
Expression patterns of the lysophospholipid receptor genes during mouse early development |
| Publication |
Dev. Dyn., vol. 237, 3280-3294 (2008) |
| Authors |
Nakasaki T, Tanaka T, Okudaira S, Hirosawa M, Umemoto E, Otani K, Jin S, Bai Z, Hayasaka H, Fukui Y, Aozasa K, Fujita N, Tsuruo T, Ozono K, Aoki J, Miyasaka M |
| Title |
Involvement of the Lysophosphatidic Acid-Generating Enzyme Autotaxin in Lymphocyte-Endothelial Cell Interactions |
| Publication |
Am. J. Pathol., vol. 173, 1566-1576 (2008) |
| Authors |
Kano K, Arima N, Ohgami M, Aoki J |
| Title |
LPA and its analogs-attractive tools for elucidation of LPA biology and drug development |
| Publication |
Curr. Med. Chem., vol. 15, 2122-2131 (2008) |
| Authors |
Masuda A, Nakamura K, Izutsu K, Igarashi K, Ohkawa R, Jona M, Higashi K, Yokota H, Okudaira S, Kishimoto T, Watanabe T, Koike Y, Ikeda H, Kozai Y, Kurokawa M, Aoki J, Y. Yatomi |
| Title |
Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma |
| Publication |
Br. J. Haematol., vol. 143, 60-70 (2008) |
| Authors |
Aoki J, Inoue A, Okudaira S |
| Title |
Two pathways for lysophosphatidic acid production |
| Publication |
Biochim. Biophys. Acta, vol. 1781, 513-518 (2008) |
| Authors |
Kanamori T, Inoue T, Sakamoto T, Gengyo-Ando K, Tsujimoto M, Mitani S, Sawa H, Aoki J, Arai H |
| Title |
Beta-catenin asymmetry is regulated by PLA1 and retrograde traffic in C. elegans stem cell divisions |
| Publication |
EMBO J., vol. 27, 1647-1657 (2008) |
| Authors |
Inoue M, Xie W, Matsushita Y, Chun J, Aoki J, Ueda H |
| Title |
Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid |
| Publication |
Neuroscience, vol. 152, 296-298 (2008) |
| Authors |
Inoue M, Ma L, Aoki J, Chun J, Ueda H |
| Title |
Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain |
| Publication |
Mol. Pain, vol. 8, 4-6 (2008) |
| Authors |
Nakamura K, Nangaku M, Ohkawa R, Okubo S, Yokota H, Ikeda H, Aoki J, Yatomi Y |
| Title |
Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome |
| Publication |
Clin. Chem. Lab. Med., vol. 46, 150-151 (2008) |
| Authors |
Kono N, Inoue T, Yoshida Y, Sato H, Matsusue T, Itabe H, Niki E, Aoki J, Arai H |
| Title |
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo |
| Publication |
J. Biol. Chem., vol. 283, 1628-1636 (2008) |
| Authors |
Nakamura, K., Igarashi, K., Ide, K., Ohkawa, R., Okubo, S., Yokota, H., Masuda, A., Oshima, N., Takeuchi, T., Nangaku, M., Okudaira, S., Arai, H., Ikeda, H., Aoki, J., Yatomi, Y. |
| Title |
Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation |
| Publication |
Clin. Chim. Acta, vol. 388, 51-58 (2008) |
| Authors |
Yamaguchi, N., Koizumi, H., Aoki, J., Natori, Y., Nishikawa, K., Natori, Y., Takanezawa, Y., and Arai, H. |
| Title |
Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification |
| Publication |
Genes Cells, vol. 12, 1153-1161 (2007) |
| Authors |
Watanabe, N., Ikeda, H., Nakamura, K., Ohkawa, R., Kume, Y., Tomiya, T., Tejima, K., Nishikawa, T., Arai, M., Yanase, M., Aoki, J., Arai, H., Omata, M., Fujiwara, K., and Yatomi, Y. |
| Title |
Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity |
| Publication |
Life Sci., vol. 81, 1009-1015 (2007) |
| Authors |
Watanabe, N., Ikeda, H., Nakamura, K., Ohkawa, R., Kume, Y., Aoki, J., Hama, K., Okudaira, S., Tanaka, M., Tomiya, T., Yanase, M., Tejima, K., Nishikawa, T., Arai, M., Arai, H., Omata, M., Fujiwara, K., and Yatomi, Y. |
| Title |
Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C |
| Publication |
J. Clin. Gastroenterol., vol. 41, 616-623 (2007) |
| Authors |
Umemura, K., Kato, I., Hirashima, Y., Ishii, Y., Inoue, T., Aoki, J., Kono, N., Oya, T., Hayashi, N., Hamada, H., Endo, S., Oda, M., Arai, H., Kinouchi, H., Hiraga, K. |
| Title |
Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia |
| Publication |
Stroke, vol. 38, 1063-1068 (2007) |
| Authors |
Tokumura, A., Kume, T., Fukuzawa, K., Tahara, M., Tasaka, K., Aoki, J., Arai, H., Yasuda, K., Kanzaki, H. |
| Title |
Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity |
| Publication |
Life Sci., vol. 80, 1641-1649 (2007) |
| Authors |
Savaskan, N. E., Rocha, L., Kotter, M. R., Baer, A., Lubec, G., van Meeteren, L. A., Kishi, Y., Aoki, J., Moolenaar, W. H., Nitsch, R., Brauer, A. U. |
| Title |
Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma |
| Publication |
Cell. Mol. Life Sci., vol. 64, 230-243 (2007) |
| Authors |
Satoh, Y., Ohkawa, R., Nakamura, K., Higashi, K., Kaneko, M., Yokota, H., Aoki, J., Arai, H., Yuasa, Y., Yatomi, Y. |
| Title |
Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6 |
| Publication |
Eur. J. Haematol., vol. 78, 510-517 (2007) |
| Authors |
Ohuchi, H., Hayashibara, Y., Matsuda, H., Onoi, M., Mitsumori, M., Tanaka, M., Aoki, J., Arai, H., Noji, S. |
| Title |
Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development |
| Publication |
Dev. Dyn., vol. 236, 1134-1143 (2007) |
| Authors |
Nakamura, K., Ohkawa, R., Okubo, S., Tozuka, M., Okada, M., Aoki, S., Aoki, J., Arai, H., Ikeda, H., Yatomi, Y. |
| Title |
Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients |
| Publication |
Ann. Clin. Biochem., vol. 44, 549-556 (2007) |
| Authors |
Nakamura, K., Ohkawa, R., Okubo, S., Tozuka, M., Okada, M., Aoki, S., Aoki, J., Arai, H., Ikeda, H., Yatomi, Y. |
| Title |
Measurement of lysophospholipase D/autotaxin activity in human serum samples |
| Publication |
Clin. Biochem., vol. 40, 274-277 (2007) |
| Authors |
Morikawa, R., Tsujimoto, M., Arai, H., Aoki, J. |
| Title |
Phospholipase A(1) assays using a radiolabeled substrate and mass spectrometry |
| Publication |
Methods Enzymol., vol. 434, 1-13 (2007) |
| Authors |
Mori, K., Kitayama, J., Aoki, J., Kishi, Y., Shida, D., Yamashita, H., Arai, H., Nagawa, H. |
| Title |
Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD) |
| Publication |
Virchows Arch., vol. 451, 47-56 (2007) |
| Authors |
Kono, N., Inoue, T., Yoshida, Y., Sato, H., Matsusue, T., Itabe, H., Niki, E., Aoki, J., Arai, H. |
| Title |
Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo |
| Publication |
J. Biol. Chem., vol. 283, 1628-1636 (2007) |
| Authors |
Hama, K., Aoki, J., Inoue, A., Endo, T., Amano, T., Motoki, R., Kanai, M., Ye, X., Chun, J., Matsuki, N., Suzuki, H., Shibasaki, M., Arai, H. |
| Title |
Embryo spacing and implantation timing are differentially regulated by LPA3-mediated lysophosphatidic acid signaling in mice |
| Publication |
Biol. Reprod., vol. 77, 954-959 (2007) |
| Authors |
Aoki, J., Inoue, A., Makide, K., Saiki, N., Arai, H. |
| Title |
Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family |
| Publication |
Biochimie, vol. 89, 197-204 (2007) |
| Authors |
Junken Aoki |
| Title |
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid |
| Publication |
Korean Pharmaceutical Society Annual Meeting, Seoul, Korea (2007/11/9) |
| Authors |
Junken Aoki |
| Title |
Recent progress in study of lysophosphatidic acid production |
| Publication |
10th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases, Montreal, Canada (2007/7/16-19) |
| Authors |
Asuka Inoue, Kotaro Hama, Hiroyuki Arai, Junken Aoki |
| Title |
Promoted Implantation in vivo by a Novel Lysophosphatidic Acid-Producing Enzyme |
| Publication |
The 5th Korea-Japan Conference on Cellular Signaling for Young Scientists, Gyeongju, Korea (2007/7/9-12) |
| Authors |
Tomoko Endo, Kotaro Hama, Mayuko Ishida, Ryo Taguchi, Hiroyuki Arai, Junken Aoki |
| Title |
Lysophosphatidylmethanol as a novel LPA receptor agonist |
| Publication |
The 5th Korea-Japan Conference on Cellular Signaling for Young Scientists, Gyeongju, Korea (2007/7/9-12) |
| Authors |
Junken Aoki |
| Title |
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid |
| Publication |
The 3rd International conference on phospholipases A2 and lipid mediators, Sorrento, Italy (2007/5/9-12) |
| Authors |
Junken Aoki |
| Title |
Patho-physiological role of autotaxin |
| Publication |
2007 FASEB Summer Research Conferences - Lysophospholipid Mediators in Health and Disease, Tucson, Arizona, USA (2007/6/9-14) |
| Authors |
Naoko Watanabe, Hitoshi Ikeda, Kazuhiro Nakamura, Ryunosuke Ohkawa, Yukio Kume, Junken Aoki, Kotaro Hama, Shinichi Okudaira, Masayuki Tanaka, Mikio Yanase, Kayo Nagashima, Tomoaki Tomiya, Kazuaki Tejima, Takako Nishikawa, Hiroyuki Arai, Masao Omata, Kenji Fujiwara, Yutaka Yatomi |
| Title |
Plasma lysophosphatidic acid is increased in liver fibrosis in rats and human with enhanced serum autotaxin level |
| Publication |
J. Clin. Gastroenterol., vol. 41, 616-623 (2007) |
| Authors |
Akira Tokumura, Tetsuya Kume, Kenji Fukuzawa, Masahiro Tahara, Keiichi Tasaka, Junken Aoki, Hiroyuki Arai, Katsuhiko Yasuda, Hideharu Kanzaki |
| Title |
Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity |
| Publication |
Life Sciences, vol. 80, 1641-1649 (2007) |
| Authors |
Hideyo Ohuchi, Yasunori Hayashibara, Hironao Matsuda, Motoyoshi Onoi, Masayuki Mitsumori, Masayuki Tanaka, Junken Aoki, Hiroyuki Arai, Sumihare Noji |
| Title |
Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development |
| Publication |
Developmental Dynamics, vol. 236, 1134-1143 (2007) |
| Authors |
Kazuhiro Nakamura, Ryunosuke Ohkawa, Shigeo Okubo, Minoru Tozuka, Mitsumasa Okada, Shinya Aoki, Junken Aoki, Hiroyuki Arai, Hitoshi Ikeda, Yutaka Yatomi |
| Title |
Measurement of lysophospholipase D/autotaxin activity in human serum samples |
| Publication |
Clinical Biochemistry, vol. 40, 274-277 (2007) |
| Authors |
Nicolai E. Savaskan, Linda Rocha, Mark R. Kotter, Gert Lubec, Alexandra Baer, Laurens van Meeteren, Yasuhiro Kishi, Junken Aoki, Wouter H. Moolenaar, Robert Nitsch, Anja U. Bruer |
| Title |
Autotaxin (NPP-2) in the brain: Cell type-specific expression and regulation during development and after neurotrauma |
| Publication |
Cell. Mol. Life Sci., vol. 64, 230-243 (2007) |
| Authors |
Asuka Inoue, Junken Aoki |
| Title |
Phospholipase A1s - Structure, distribution and function- |
| Publication |
Future Lipidology., vol. 1, 687-700 (2006) |
| Authors |
Mitsuhiro Ohtsuki, Yoshitaka Taketomi, Satoru Arata, Seiko Masuda, Yukio Ishikawa, Toshiharu Ishii, Yasukazu Takanezawa, Junken Aoki, Hiroyuki Arai, Kei Yamamoto, Ichiro Kudo, Makoto Murakami |
| Title |
Transgenic Expression of Group V, but not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality due to Lung Dysfunction |
| Publication |
J. Biol. Chem., vol. 281, 36420-36433 (2006) |
| Authors |
Hiroharu Yamashita, Joji Kitayama, Dai Shida, Makoto Ishikawa, Kotaro Hama, Junken Aoki, Hiroyuki Arai, Hirokazu Nagawa |
| Title |
Differential expression of lysophosphatidic acid receptor-2 in intestinal and diffuse type gastric cancer |
| Publication |
J. Surg. Oncol., vol. 93, 30-35 (2006) |
| Authors |
Nobuo Watanabe, Jaroslaw W. Zmijewski, Wakako Takabe, Makiko Umezu-Goto, Claire LeGoffe, Azusa Sekine, Aimee Landar, Akira Watanabe, Junken Aoki, Hiroyuki Arai, Tatsuhiko Kodama, Michael P. Murphy, Raman Kalyanaraman, Victor M. Darley-Usmar and Noriko Noguchi |
| Title |
Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells |
| Publication |
Am. J. Pathol., vol. 168, 1737-1748 (2006) |
| Authors |
Yutaka Masuda, Hiroyuki Itabe, Miho Odaki, Kotaro Hama, Yasuyuki Fujimoto, Masahiro Mori, Naoko, Junken Aoki, Hiroyuki Arai, Tatsuya Takano |
| Title |
Adipose differentiation-related protein is degraded through the proteasome-dependent pathway during regression of lipid-storing cells |
| Publication |
J. Lipid Res., vol. 47, 87-98 (2006) |
| Authors |
Lian Qian, Yong Xu, Ted Simper, Guowei Jiang, Junken Aoki, Makiko Umezu-Goto, Hiroyuki Arai, Shuangxing Yu, Gordon B. Mills, Ryoko Tsukahara, Natalia Makarova, Yuko Fujiwara, Gabor Tigyi, Glenn D. Prestwich |
| Title |
Phosphorothioate Analogues of Alkyl Lysophosphatidic Acid as LPA3 Receptor-Selective Agonists |
| Publication |
ChemMedChem., vol. 1, 376-383 (2006) |
| Authors |
Yasuhiro Kishi, Shinichi Okudaira, Masayuki Tanaka, Kotaro Hama, Dai Shida, Joji Kitayama, Takao Yamori, Junken Aoki, Takahiro Fujimaki, Hiroyuki Arai |
| Title |
Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcoholine to lysophosphatidic acid |
| Publication |
J. Biol. Chem., vol. 281, 17492-17500 (2006) |
| Authors |
Hiroaki Okazaki, Junichi Osuga, Masaki Igarashi, Makiko Tajima, Makiko Nishi, Motohiro Sekiya, Sachiko Okazaki, Naoya Yahagi, Kazuhisa Tsukamoto, Michiyo Amemiya-Kudo, Takashi Matsuzaka, Hitoshi Shimano, Nobuhiro Yamada, Junken Aoki, Rei Morikawa, Yasukazu Takanezawa, Hiroyuki Arai, Ryozo Nagai, Takashi Kadowaki, Shun Ishibashi |
| Title |
Triglyceride hydrolase-2, a novel paralogue of triglyceride hydrolase, is regulated by nutritional conditions in adipose tissue |
| Publication |
DIABETES, vol. 55, 2091-2097 (2006) |
| Authors |
Kotaro Hama, Junken Aoki, Koji Bandoh, Asuka Inoue, Tomoko Endo, Tomokazu, Amano, Hiroshi Suzuki, Hiroyuki Arai |
| Title |
Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus |
| Publication |
Life Sciences, vol. 79, 1736-1740 (2006) |
| Authors |
Masayuki Tanaka, Shinichi Okudaira, Yasuhiro Kishi, Ryunosuke Ohkawa, Sachiko Iseki, Masato Ota, Sumihare Noji, Yutaka Yatomi, Junken Aoki, Hiroyuki Arai |
| Title |
Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid |
| Publication |
J. Biol. Chem., vol. 281, 25822-25830 (2006) |
| Authors |
Satomi Tsuda, Shinichi Okudaira, Keiko Moriya-Ito, Chie Shimamoto, Masayuki Tanaka, Junken Aoki, Hiroyuki Arai, Kimiko Murakami-Murofushi, Tetsuyuki Kobayashi |
| Title |
Cyclic phosphatidic acid is produced by autotaxin in blood |
| Publication |
J. Biol. Chem., vol. 281, 26081-26088 (2006) |
| Authors |
Tomoko Endo, Kotaro Hama, Junken Aoki, Shinobu Ikeda, Rie Motoki, Motomu Kanai, Norio Matsuki, Masakatsu Shibasaki, Hiroyuki Arai |
| Title |
Lysophosphatidylmethanol as a novel LPA receptor agonist |
| Publication |
20th IUBMB Congress of Biochemistry and Molecular Biology, Kyoto, Japan (2006/6/21) |
| Authors |
Asuka Inoue, Kotaro Hama, Junken Aoki, Hiroyuki Arai |
| Title |
Enhancement of Implantation by a Novel Lysophosphatidic Acid-Producing Enzyme in vivo |
| Publication |
20th IUBMB Congress of Biochemistry and Molecular Biology, Kyoto, Japan (2006/6/21) |
| Authors |
Masayuki Tanaka, Shinichi Okudaira, Yasuhiro Kishi, Ryunosuke Ohkawa, Sachiko Iseki, Masato Ota, Sumihare Noji, Yutaka Yatomi, Junken Aoki, Hiroyuki Arai |
| Title |
Physiological role of autotaxin in mouse development |
| Publication |
20th IUBMB Congress of Biochemistry and Molecular Biology, Kyoto, Japan (2006/6/21) |
| Authors |
Takahiro Kanamori, Junken Aoki, Takao Inoue, Taro Sakamoto, Masaki Ishikawa, Ryo Taguchi, Yasuhito Nakagawa, Masafumi Tsujimoto, Hiroyuki Arai |
| Title |
Intracellular phospholipase A1 is required for epithelial integrity in C.elegans |
| Publication |
20th IUBMB Congress of Biochemistry and Molecular Biology, Kyoto, Japan (2006/6/21) |
| Authors |
Satomi Tsuda, Keiko Moriya-Ito, Shinichi Okudaira, Masayuki Tanaka, Yasukazu Takanezawa, Junken Aoki, Hiroyuki Arai, Kimiko Murakami-Murofushi, Tetsuyuki Kobayashi |
| Title |
Cyclic phosphatidic acid is produced by autotaxin in mammalian blood |
| Publication |
20th IUBMB Congress of Biochemistry and Molecular Biology, Kyoto, Japan (2006/6/21) |
| Authors |
Junken Aoki, Takahiro Kanamori, Rei Morikawa, Takao Inoue, Hiroyuki Arai |
| Title |
Intracellular phospholipase A1 |
| Publication |
20th IUBMB Congress of Biochemistry and Molecular Biology "Symposia S44 -Lysophospholipid mediators from health to disease", Kyoto, Japan (2006/6/21) |
| Authors |
Junken Aoki |
| Title |
Structure and function of a novel phospholipase A1 family |
| Publication |
3rd Lipidomics Meeting "From Lipid Analysis to Genetic Disorders", Marseille, France (2006/5/12) |
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