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Mechanism of higher-order epigenome regulation and its medical significance

Research Project Outline

In addition to DNA methylation and histone modification, this study focuses on higher-order epigenome mechanism, especially chromatin loop and nuclear domain formation for essential gene control. From this viewpoint, we will present the spatiotemporal models of disease-related gene loci, leading to the generation of new technologies of cell identification for medical diagnosis and therapy.

Research Director
MitsuyoshiNakao
Affiliation
Professor, Kumamoto University
Research Started
2011
Status
ongoing
Research Area
Development of Fundamental Technologies for Diagnosis and Therapy Based upon Epigenome Analysis
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