Development of genomic technologies to explore human epigenetic regulation

Research Project Outline

Our body consists of more than 250 cell types. While each cell has the same DNA sequence, protein modifications and their binding pattern (so called epigenetic information) defines the specificity of each cell type. The aim of this study is to develop the new standard method to analyze whole picture of epigenetic information and use the method to explore whole-genome epigenetic information of various endothelial cell species. Our ultimate goal is to contribute to the International Human Epigenome Consortium through both epigenomics data and technology development. These data and methods are expected to contribute to basic research and drug discovery as well.

Research Director
KatsuhikoShirahige
Affiliation
Professor, University of Tokyo
Research Started
2011
Status
ongoing
Research Area
Development of Fundamental Technologies for Diagnosis and Therapy Based upon Epigenome Analysis
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