In vivo optical imaging and optical manipulation by using a novel multiphoton microscopy with advanced ultrashort light pulses and their application for cancer research and medicine

Research Project Outline

In order to establish an innovative “in vivo” optical imaging, we will develop a novel non-linear optical microscopy by combining with adaptive optics and advanced light sources including an optical parametric oscillator, a supercontinuum light source and a small size femtosecond mode-locked laser source. The multiphoton microscopy will enable real-time image of multiple events in cancer cells and their microenvironment, and our research will facilitate development of novel light sources.