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Publications

Review articles and books Conference presentations 

Papers

2015 
Kohki Fujikawa, Akihiko Koizumi, Masakazu Hachisu, Akira Seko, Yoichi Takeda and Yukishige Ito
Construction of a High-Mannose-Type Glycan Library by a Renewed Top-Down Chemo-Enzymatic Approach
Chem. Eur. J. 2015, 21, 3224-3233.
 
Katsuhiko Suzuki, Shusaku Daikoku, Sang-Hyun Son, Yukishige Ito, and Osamu Kanie
Synthetic study of 3-fluorinated sialic acid derivatives
Carbohydrate Research 2015, 406, 1-9.  
2014
Fang Zhang, Mominul M.Hoque, Jiandong Jiang, Kaoru Suzuki, Masaru Tsunoda, Yoichi Takeda, Yukishige Ito, Gota Kawai, Haruo Tanaka and Akio Takénaka
The Characteristic Structure of Anti-HIV Actinohivin in Complex with Three HMTG D1 Chains of HIV-gp120
ChemBioChem 2014, 15, 2766-2773 
S. Park, I. Jang, C. Zuber, Y.Lee, J.W. Cho, I. Matsuo, Y. Ito, and J. Roth
ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase
Histochem. Cell Biol. 2014, 142, 153-169. 
Masafumi Sakono, Akira Seko, Yoichi Takeda, and Yukishige Ito
PDI family protein ERp29 forms 1:1 complex with lectin chaperone calreticulin
Biochem. Biophys. Res. Commun. 2014, 452, 27-31.  
Shusaku Daikoku, Akira Seko, Yukishige Ito, and Osamu Kanie
Glycan structure and site of glycosylation in the ER-resident glycoprotein, uridine 5'-diphosphate-glucose: glycoprotein glucosyltransferases 1 from rat, porcine, bovine, and human
Biochem. Biophys. Res. Commun. 2014, 451, 356-360.
Shogo Iwamoto, Yuta Kasahara, Ken-ichi Kamei, Akira Seko, Yoichi Takeda, Yukishige Ito, and Ichiro Matsuo
Measurement of endo-α-mannosidase activity using a fluorescently labeled oligosaccharide derivatives
Biosci. Biotech. Biochem. 2014, 78, 927-936. 
Masafumi Sakono, Akira Seko, Yoichi Takeda, Jun-ichi Aikawa, Masakazu Hachisu, Akihiko Koizumi, Kohki Fujikawa, and Yukishige Ito
Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions
Biochimica et Biophysica Acta (BBA) - General Subjects 2014, 1840, 2904–2913.  
Jun-ichi Aikawa, Yoichi Takeda, Ichiro Matsuo, and Yukishige Ito
Trimming of glucosylated N-glycans by human ER α1,2-mannosidase I
J. Biochem. 2014, 155, 375–384.  
Masafumi Sakono, Akira Seko, Yoichi Takeda, Jun-ichi Aikawa, Masakazu Hachisu, Akihiko Koizumi, Kohki Fujikawa, and Yukishige Ito
Glycan specificity of a testis-specific lectin chaperone calmegin and effects of hydrophobic interactions
Biochimica et Biophysica Acta (BBA) - General Subjects 2014, 1840, 2904-2913. 
Simone Dedola, Masayuki Izumi, Yutaka Makimura, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, and Yasuhiro Kajihara
Folding of Synthetic Homogeneous Glycoproteins in the Presence of a Glycoprotein Folding Sensor Enzyme
Angewandte Chemie International Edition 2014, 53, 2883–2887. 
Yoichi Takeda, Akira Seko, Masakazu Hachisu, Shusaku Daikoku, Masayuki Izumi, Akihiko Koizumi, Kohki Fujikawa, Yasuhiro Kajihara, and Yukishige Ito
Both Isoforms of Human UDP-glucose:glycoprotein Glucosyltransferase are Enzymatically Active
Glycobiology 2014, 24, 344–350.  
Sang-Hyun Son, Shusaku Daikoku, Atsuko Ohtake, Katsuhiko Suzuki, Kazuya Kabayama, Yukishige Ito and Osamu Kanie
Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ
Chem. Commun. 2014, 50, 3010–3013.  
2013
Sophon Kaeothip, Akihiro Ishiwata, Tasuku Ito, Shinya Fushinobu, Kiyotaka Fujita and Yukishige Ito
Preparation of p-nitrophenyl β-l-arabinofuranoside as a substrate of β-l-arabinofuranosidase
Carbohydrate Res. 2013, 382, 95–100.
Yuki Shioiri, Katsuhiko Suzuki, Shusaku Daikoku, Ayako Kurimoto, Yukishige Ito and Osamu Kanie
Stereospecific generation and analysis of α- and β-hemiacetals of monosaccharides in gas phase
Carbohydrate Res. 2013, 382, 43–51.  
Sophon Kaeothip, Akihiro Ishiwata and Yukishige Ito
Stereoselective synthesis of Arabidopsis CLAVATA3(CLV3) glycopeptide, unique protein post-translational modifications of secreted peptide hormone in plant
Org. Biomol. Chem. 2013, 11, 5892-5907.
 
Atsuko Ohtake, Shusaku Daikoku, Katsuhiko Suzuki, Yukishige Ito and Osamu Kanie
Analysis of the cellular dynamics of fluorescently tagged glycosphingolipids by using a nanoLC-MS/MS platform
Anal. Chem. 2013, 85, 8475-8482.
Akihiko Koizumi, Ichiro Matsuo, Maki Takatani, Akira Seko, Masakazu Hachisu, Yoichi Takeda, Yukishige Ito
Top-Down Chemoenzymatic Approach to a High-Mannose-Type Glycan Library: Synthesis of a Common Precursor and Its Enzymatic Trimming
Angewandte Chemie 2013, 52, 7426–7431.
 
Yoichi Takeda, Akira Seko, Masafumi Sakono, Masakazu Hachisu, Akihiko Koizumi, Kohki Fujikawa, Yukishige Ito
Parallel Quantification of Lectin–Glycan Interaction using Ultrafiltration
Carbohydrate Res. 2013, 375, 112-117.

Shino Manabe and Yukishige Ito
Hafnium(IV) Tetratriflate as a Glycosyl Fluoride Activation Reagent
J. Org. Chem. 2013, 78, 4568–4572.
 2012
Shogo Iwamoto, Miho Isoyama, Makoto Hirano, Kenta Yamaya, Yukishige Ito, Ichiro Matsuo, and Kiichiro Totani
Reconstructed glycan profile for evaluation of operating status of the endoplasmic reticulum glycoprotein quality control
Glycobiology 2012, 23, 121-131.

Yutaka Makimura, Tatsuto Kiuchi, Masayuki Izumi, Simone Dedola, Yukishige Ito and Yasuhiro Kajihara
Efficient synthesis of glycopeptide-α-thioesters with a high-mannose type oligosaccharide by means of tert-Boc-solid phase peptide synthesis
Carbohydrate Res. 2012, 364, 41-48.
 
Masafumi Sakono, Akira Seko, Yoichi Takeda, Masakazu Hachisu, and Yukishige Ito
Biophysical properties of UDP-glucose:glycoprotein glucosyltransferase, a folding sensor enzyme in the ER, delineated by synthetic probes
Biochem. Biophys. Res. Commun. 2012, 426, 504-510..
 
Katsuhiko Suzuki, Atsuko Ohtake, Yukishige Ito and Osamu Kanie
Synthesis of a fluorescently tagged sialic acid analogue useful for live-cell imaging
Chem. Comm. 2012, 48, 9744-9746.
 
Katsuhiko Suzuki, Yukishige Ito,Osamu Kanie
An improved method for the synthesis of protected glycosyl fluorides from
thioglycosides using N,N-diethylaminosulfur trifluoride (DAST)

Carbohydrate Res. 2012, 359, 81-91.
  
M.Izumi, Y. Makimura, S. Dedola, A. Seko, A. Kanamori, M. Sakono, Y. Ito, Y. Kajihara.
Chemical Synthesis of intentionally Misfolded homogeneous Glycoprotein: a unique approach for the study of glycoprotein quality control
J. Am. Chem. Soc. 2012, 134, 7238-7241.
   
Yukishige Ito, Yoichi Takeda
Analysis of glycoprotein processing in the endoplasmic reticulum using synthesis oligosaccharides
Proc. Jpn. Acad., Ser. 2012, 88, 31-40.
 
Jun-ichi Aikawa & Ichiro Matsuo and Yukishige Ito
In vitro mannose trimming property of human ER α-1,2 mannosidase I
Glycoconj J. 2012, 29, 35-45.
  
Yu Nakagawa, Takashi Doi, K. Takegoshi, Yasuhiro Igarashi, and Yukishige Ito
Solid-state NMR analysis of calcium and D-mannose binding of BMY-28864, a water-soluble analogue of pradimicin A
Bioorganic & Medicinal Chemistry Letters. 2012, 22, 1040-1043.
 
 2011
Yu Nakagawa, Takashi Doi, Yuichi Masuda, K. Tagegoshi, Yasuhiro Igarashi, and Yukishige Ito
Mapping of the primary mannose binding site of Pradimicin A
J. Am. Chem. Soc.. 2011, 133, 17485-17493.

Shino Manabe, Kazuyuki Ishii, Hiroko Satoh, Yukishige Ito
Substituent effects in endocyclic cleavage-recyclization anomerization reaction of pyranosides
Tetrahedron. 2011, 67, 9966-9974.
  
R. Pejchal, K.J. Doores, L.M. Walker, R. Khayat, P.S. Huang, S.K. Wang, R.L. Stanfield, J.P. Julien, A. Ramos, M. Crispin, R. Depetris, U. Katpally, A. Marozsan, A. Cupo, S. Maloveste, Y. Liu, R. McBride, Y. Ito, R.W. Sanders, C. Ogohara, J.C. Paulson, T. Feizi, C.N. Scanlan, C.H. Wong, J.P. Moore, W.C. Olson, A.B. Ward, P. Poignard, W.R. Schief, D.R. Burton, and I.A. Wilson
A Potent and Broad Neutralizing Antibody Recognizes and Penetrates tne HIV Glycan Shield
Science 2011, 334, 1097-1103.
  
A. Ishiwata, A. Sakurai, Y. Nishimiya, S. Tsuda, Y. Ito
Synthetic Study and Structural Analysis of the Antifreeze Agent Xylomannan from Upis ceramboides
J. Am. Chem. Soc.. 2011, 133, 19524-19535
.  
Kanie,O. Kanie,Y. Daikoku,S.Shioiri,Y. Kurimoto,A. Mutsuga,S. Goto,S. Ito,Y.Suzuki,K.
Multistage MS/MS information obtained by deconvolution of energy-resolved mass spectra acquired by triple-quadrupole mass spectrometry
Rapid Commun. Mass Spectrom. 2011, 25, 1617-1624
K. Totani, H. Miyazawa, S. Kurata, Y. Ito
Magnetic beads-assisted mild enrichment procedure for weak-binding lectins
Analytical Biochemistry. 2011, 411, 50-57
Shino Manabe, Kazuyuki Ishii, Yukishige Ito
N-Benzyl-2,3-trans-carbamate-bearing glycosyl donors for 1,2-cis-selective glycosylation reactions
Eur. J. Org. Chem.. 2011, 2011, 497-516.
  
Akihiro Ishiwata, Yukishige Ito
Synthesis of docosasaccharide arabinan motif of mycobacterial cell wall
J. Am. Chem. Soc. 2011, 133, 2275-2291.
 
Toshiki Nokami, Yuki Nozaki, Yoshihiro Saigusa, Akito Shibuya, Shino Manabe, Yukishige Ito, and Jun-ichi Yoshida
Glycosyl sulfonium lons as storable intermediates for glycosylations
Org. Lett. 2011, 13, 1544-1547
S. Daikoku, Y. Ono, A. Ohtake, Y. Hasegawa, E. Fukusaki, K. Suzuki, Y. Ito, S. Goto and O. Kanie
Fluorescence-monitored zero dead-volume nanoLC-microESI-QIT-TOF MS for analysis of fluorescently tagged glycosphingolipids.
Analyst. 2011, 136, 1046-1050
.  
Y.J. Lee, A. Kubota, A. Ishiwata and Y. Ito
Synthesis of Pseudaminic Acid, a Unique Nonulopyranoside Derived from Pathogenic Bacteria through 6-deoxy-AltdiNAc
Tetrahedron Letters. 2011, 52, 418-421
.  
 2010
Yamamoto-Hino,M. Kanie,Y. Awano,W. Aoki-Kinoshita,K F. Yano,H. Nishihara,S. Okano,H. Ueda,R. Kanie,O. Goto,S.
Identification of genes required for neural-specific glycosylation using functional genomics
PLoS Genet. 2010, 6, e1001254.
 
Y. Funakoshi, Y. Negishi, J.P. Gergen, J. Seino, K. Ishii, W.J. Lennarz, I. Matsuo, Y. Ito, N. Taniguchi, and T. Suzuki
 Evidence for an Essential Deglycosylation-Independent Activity of PNGase in Drosophila melanogaster
PLos ONE 2010, 5, 1-12
.  
A. Ishiwata,Y.J. Lee, and Y. Ito
Recent advances in stereoselective glycosylation through intramolecular aglycon delivery
Org. Biomol. Chem. 2010, 8, 3596-3608
.  
S. Hanashima, K. Sato, Y. Naito, H. Takematsu, Y. Kozutsumi, Y. Ito, and Y. Yamaguchi
Synthesis and binding analysis of unique AG2 pentasaccharide to human Siglec-2 using NMR techniques
Bioorg. Med. Chem. 2010, 18, 3720-3725
.  
A. Ishiwata, A. Sakurai, K. Durr, and Y. Ito
Effects of frozen conditions on stereoselectivity and velocity of O-glycosylation reactions
Bioorg. Med. Chem. 2010, 18, 3687-3695
.  
Y. Ihara, S. Manabe, M. Ikezaki, Y. Inai, I.L. Matsui, Y. Ohta, E. Muroi, and Y. Ito
C-mannosylated peptides derived from the thrombospondin type 1 repeat interact with Hsc70 to modulate its signaling in RAW264.7 cells
Glycobiology. 2010, 20, 1298-1310
.  
A. Miyagawa, K. Totani, I. Matsuo, and Y. Ito
Promiscuous activity of ER glucosidase II discovered through donor specificity analysis of UGGT
Biochem. Biophys. Res. Commun. 2010, 403, 322-328.
Kaoru Mikami, Daisuke Yamaguchi, Hiroaki Tateno, Dan Hu, Sheng-Ying Qin, Norihito Kawasaki, Michiyuki Yamada, Naoki Matsumoto, Jun Hirabayashi, Yukishige Ito, and Kazuo Yamamoto
The sugar-binding ability of human OS-9 and its involvement in ER-associated degradation
Glycobiology 2010, 20, 310-321
.  
Motohide Murate, Tomohiro Hayakawa, Kumiko Ishii, Hironori Inadome, Peter Greimel, Masaki Watanabe, Yasuko Nagatsuka, Kazuki Ito, Yukishige Ito, Hiroshi Takahashi, Yoshio Hirabayashi, and Toshihide Kobayashi
Phosphatidylglucoside forms specific lipid domains on the outer leaflet of the plasma membrane
Biochemistry 2010, 49, 4732-4739
.  

Review articles and books

2014
Yoichi Takeda, Ichiro Matsuo
Isothermal Calorimetric Analysis of Lectin–Sugar Interaction
Lectins, Vol.1200 (2014) pp.207-214
 
Yoichi Takeda, Akira Seko, and Yukishige Ito
Functional Analysis of Endoplasmic Reticulum Glucosyltransderase (UGGT) Using Synthetic Glycans
Trends in Glycoscience and Glycotechnology, Vol.26 (2014) No.151 pp.107-118
2013
Yukishige Ito, Yoichi Takeda
Deciphering the Roles of Glycan Processing in Glycoprotein Quality Control through Organic Synthesis
Biosci Biotechnol Biochem. 2013, 77, 2331-2338.
   
Masayuki Izumi,Tatsuto Kiuchi, Yukishige Ito, and Yasuhiro Kajihara
Misfolded Glycoproteins as Probes for Analysis of Folding Sensor Enzyme UDP-Glucose : Glycoprotein Glucosyltransferase
Trends in Glycoscience and Glycotechnology, Vol.25 (2013) No.141 pp.1-12
2010
Y. Ito
My Stroll in the Backyard of Carbohydrate Chemistry
Trends in Glycoscience and Glycotechnology, Vol.22 (2010) No.125 pp.119-140  
 
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Conference presentations

 2014
Yoichi Takeda, Akira Seko, Keiichirou Ohara, Masakazu Hachisu, Kohki Fujikawa, Ning Wang, Yukishige Ito
Catalytic Domain of UDP-Glc: Glycoprotein Glucosyltransferase; Functional Analysis using Synthetic Substrates
SFG & JSCR 2014 Joint Annual Meeting, Hawaii, USA, 2014.11.16-19
 
Y Ito, Y Takeda, A Seko, K Fujikawa, M Hachisu, A Koizumi, M Sakono, K Ohara, S Daikoku
Analysis of UDP-Glucose: Glycoprotein Glucosyltransferase by Synthetic Substrates
RIKEN – Max Planck Joint Research Center for Systems Chemical Biology 3rd Annual Symposium, Kreuth,
Kreuth, Germany, 2014.5.23
 
The 27th International Carbohydrate Symposium 
Y Kajihara
Chemical Synthesis of Misfolded and Correctly Folded Glycoproteins: a Unique Approach for the Study of Glycobrotein Quality Control
27th International Carbohydrate Symposium, Bangalore, India, 2014.1.12-17
 
M Hachisu, A Seko, S Daikoku, Y Takeda, M Sakono, K Ohara, K Fujikawa, N Wang, Y Ito
Design and Synthesis of Artificial Misfolded Glycoproteins as Substrates for a UDP-Glucose: Glycoprotein Glucosyltransferase
27th International Carbohydrate Symposium, Bangalore, India, 2014.1.12-17
 
A. Ishiwata, S. Kaeothip, Y Ito
Synthetic study of β-L-arabinofuranosylated glycopeptide in plant
27th International Carbohydrate Symposium, Bangalore, India, 2014.1.12-17
  
2013
Y Kajihara
Chemical Synthesis of Misfolded and Correctly Folded Glycoproteins: A Unique Approach for the Study of Glycoprotein Quality Control
1st Osaka University-EPFL International Symposium, Osaka, Japan, 2013.12.2-3
   
Ishiwata Akihiro, Kaeothip Sophon, Ito Yukishige
Synthesis of Post-translationally Modified CLAVATA3 Glycopeptides from Arabidopsis thaliana
4th Asia-Pacific International Peptide Symposium, 50th Japanese Peptide Symposium (APIPS 2013), Osaka, Japan, 2013.11.6-8
  
Y Kajihara
Chemical Synthesis of Misfolded and Correctly Folded Glycoproteins: A Unique Approach for the Study of Glycoprotein Quality Control
4th Modern Solid Phase Peptide Synthesis & its Applications Symposium, Kobe, Japan, 2013.11.2-4
    
Ito Yukishige
Glycoproteins: Research Opportunities for Synthetic Chemists
2nd International Symposium on Chemical Biology of Natural Products, Yokohama, Japan, 2013.10.28-29
 
5th Asian Communications of Glycobiology and Glycotechnology(ACGG2013) 
M Izumi, S Dedola, T Kiuchi, R Kuruma, Y Makimura, A Seko, A Kanamori, M Sakono, Y Ito, Y Kajihara
Analysis of Folding Sensor Enzyme UGGT using Chemically Synthesized Homogeneous Glycoproteins
5th Asian Communications of Glycobiology and Glycotechnology (ACGG), Khon Kaen, Thailand, 2013.10.14-18
 
K. Suzuki, A. Ohtake, S. Daikoku, Y. Ito, and O. Kanie
3-Fluorinated sialic acid derivatives; synthesis and applications
5th Asian Communications of Glycobiology and Glycotechnology (ACGG), Khon Kaen, Thailand, 2013.10.14-18
 
A. Ishiwata, S. Kaeothip, and Y. Ito
Synthetic study of all glycoforms of CLAVATA3 glycopeptide from Arabidopsis thaliana
5th Asian Communications of Glycobiology and Glycotechnology (ACGG2013), Khon Kaen, Thailand, 2013.10.14-18
  
Ito Yukishige
Glycobiology from a synthetic chemist's point of view
Biotrans 2013, Manchester, UK, 2013.7.21-25
  
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology
Yukishige Ito
Analysis and regulation of glycoprotein functions by synthetic probes
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology, Saitama, Japan, 2013.7.1-3
 
Yasuhiro Kajihara
Chemical Synthesis of Homogeneous Erythropoietin bearing M9-highmannose type oligosaccharide: A Unique Approach for the Study of Glycoprotein Quality Control
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology, Saitama, Japan, 2013.7.1-3
 
Yoichi Takeda, Seko Akira, Yukishige Ito
Functional analysis of beta-subunit of glucosidase II using synthetic high-mannose-type glycans
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology, Saitama, Japan, 2013.7.1-3
 
Akiko Kanamori, Yoichi Takeda, Akira Seko, Yukishige Ito
Accelerating Effects of Sep15 on Glucosyltransferase Activity of the Folding Sensor Protein UGGT1
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology, Saitama, Japan, 2013.7.1-3
 
Masakazu Hachisu, Akira Seko, Shusaku Daikoku, Yoichi Takeda, Kohki Fujikawa, Akihiko Koizumi, Masafumi Sakono, Yukishige Ito
Analysis of UGGT by Using Misfolded Glycoprotein Mimics
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology, Saitama, Japan, 2013.7.1-3
 
Akihiro Ishiwata, Kaeothip Sophon, Yukishige Ito
Synthetic study of β-L-arabinofuranoside derivatives from post-translationally modified glycoproteins in plants
The 3rd Austria/Japan Seminar on Comparative and Developmental Glycobiology, Saitama, Japan, 2013.7.1-3
 
22nd International Symposium on Glycoconjugates(GLYCO22) 
Seko Akira, Matsuo Ichiro, Takeda Yoichi, Koizumi Akihiko, Hachisu Masakazu, Takatani Maki, Aikawa Junichi, Ito Yukishige
Top-down synthesis of a library of high mannosetype glycans: preparation of various high mannose glycans from a
tetradeca-saccharide precursor by glycosidase digestions

22nd International Symposium on Glycoconjugates(GLYCO22), Dalian, China, 2013.6.23-28
 
Aikawa Junichi, Takeda Yoichi, Matsuo Ichiro, Ito Yukishige
In vitro catalytic properties of ER α-mannosidase I
22nd International Symposium on Glycoconjugates(GLYCO22), Dalian, China, 2013.6.23-28
 
Yukishige Ito
Analysis and Regulation of Glycoprotein Functions through Chemical Synthesis
5th Gratama Workshop, Tokyo, Japan, 2013.5.29-6.1
 
Yukishige Ito
Glycobiology from the perspective of synthetic chemistry
The 1st RIKEN-NCTU Symposium on Physical and Chemical Science, Hsinchu, Taiwan, 2013.4.26-27
  
Takeda Yoichi, Seko Akira, Ito Yukishige
In vitro analysis of the effects of β subunit of ER α-glucosidase II toward glucose trimming
10th Calreticulin Workshop, Alberta, Canada, 2013.4.10-13
 
2012
The 26th International Carbohydrate Symposium (ICS 2012)
Masayuki Izumi, Yutaka Makimura, Simone Dedola, Akira Seko, Akiko Kanamori, Masafumi Sakono, Yukishige Ito, Yasuhiro Kajihara
Chemical Synthesis of Intentionally Misfolded Homogeneous Glycoprotein: A Unique Approach for the Study of Glycoprotein Quality Control
The 26th International Carbohydrate Symposium (ICS 2012), Madrid, Spain, 2012.7.22-27
  
Simone Dedola, Yutaka Makimura, Masayuki Izumi, Akira Seko,
Yukishige Ito
, Yasuhiro Kajihara
Modified High Mannose Glyco-Crambin as Stable Mis-Folded Probes to Study in vitro Protein Folding in the Presence of UGGT
The 26th International Carbohydrate Symposium (ICS 2012), Madrid, Spain, 2012.7.22-27
  
Akiko Kanamori, Yoichi Takeda, Akira Seko, Yukishige Ito
Investigation of Effects of Sep15 on Glycosyltransferase Activity of the Folding Sensor Protein UGGT1
The 26th International Carbohydrate Symposium (ICS 2012), Madrid, Spain, 2012.7.22-27
  
Katsuhiko Suzuki, Atsuko Ohtake, Shusaku Daikoku, Yukishige Ito, Osamu Kanie
Synthesis of Fluorescently Labeled CMP-Sialic Acid Derivatives and Their Behavior in Living Cells
The 26th International Carbohydrate Symposium (ICS 2012), Madrid, Spain, 2012.7.22-27
Yuki Shioiri, Katsuhiko Suzuki, Yukishige Ito, Osamu Kanie
Resolving anomers by mass spectrometry
American Chemical Society, 243th National Meeting, San Diego, USA, 2012.3.25-29
  
Yukishige Ito
Eukaryotic and Bacterial Glycans: Research Opportunities for synthetic chemists
RIKEN-MAX PLANCK JOINT RESEARCH CENTER kick Off Symposium, Dortmund, Germany, 2012.3.5-7
  
2011
Shino Manabe, Kazuyuki Ishii, Daisuke Hashizume, Hiroyuki Koshino, Yukishige Ito
Anomerization reaction of pyranosides with 2,3-trans carbamate group
10th International Symposium on Organic Reactions (ISOR 10), Yokohama, Japan, 2011.11.21-24
  
Yukishige Ito
Synthetic challenges and opportunities around glycoprotein glycans
Glycobiology Japan-Netherland Joint Seminar 2011, Nagoya, Japan, 2011.10.10-13
  
Masafumi Sakono,Yoichi Takeda, Masakazu Hachisu, Akira Seko, Yukishige Ito
Conformational Change of Folding Sensor Enzyme UDP-Glc:Glycoprotein Glucosyltransferase (UGGT) by Internaction with Carbohydrate Substrates
The 3rd ACGG Conference, Shanghai, China, 2011.10.26-29
  
Conference on "Quality Control - Folding and Degradation of Proteins in the Endoplasmic Reticulum"
Yoichi Takeda, Akira Seko, Kiichiro Totani, Ichiro Matsuo, Yukishige Ito
Substrate Specificity Analysis of Malectin Using Synthetic High-Mannose-Type Glycans
Conference on "Quality Control - Folding and Degradation of Proteins in the Endoplasmic Reticulum", Ascona, Switzerland, 2011.9.11-16
  
Yukishige Ito, Masayuki Izumi, Yasuhiro Kajihara, Akiko Kanamori, Ichiro Matsuo, Atsushi Miyagawa, Akira Seko, Yoichi Takeda, Kiichiro Totani
Analysis of glycoprotein processing enzymes in the ER through organic synthesis
Conference on "Quality Control - Folding and Degradation of Proteins in the Endoplasmic Reticulum", Ascona, Switzerland, 2011.9.11-16
  
21st International Symposium on Glycoconjugates (GLYCO21)
Y. Ihara, M. Ikezaki, Y. Inai, I.-S.L. Matsui, E. Muroi, S. Manabe, Y. Ito
Effects of C-mannosylated TSR-derived peptides on TGF-β signaling in kidney-derived NRK-49F fibroblasts
21st International Symposium on Glycoconjugates (GLYCO21), Vienna, Austria, 2011.8.21-26
  
J.-I. Aikawa, I. Matsuo, Y. Ito
Analysis of in vitro activities of human ER α-1,2 mannosidase I on denatured glycoproteins
21st International Symposium on Glycoconjugates (GLYCO21), Vienna, Austria, 2011.8.21-26
  
K. Totani, S. Iwamoto, M. Isoyama, H. Matsushima, Y. Ito
Top-down and bottom-up approaches to understanding glycan processing in the ER
21st International Symposium on Glycoconjugates (GLYCO21), Vienna, Austria, 2011.8.21-26
  
S. Iwamoto, Y. Ito, K. Totani, I. Matsuo
The ER glycan processing profile correlates with type II diabetes
21st International Symposium on Glycoconjugates (GLYCO21), Vienna, Austria, 2011.8.21-26
  
16th European Carbohydrate Symposium
Y. Ito
Synthesis of Eukaryotic and Bacterial Glycans
16th European Carbohydrate Symposium, Sorrent,Italy, 2011.7.3-7
  
Toshiki Nokami, Yuki Nozaki, Yoshihiro Saigusa, Shino Manabe, Yukishige Ito, Jun-ichi Yoshida
Glycosyl sulfoium ions as storable glycosylation intermediates
16th European Carbohydrate Symposium, Sorrent,Italy, 2011.7.3-7
  
Shino Manabe, Yukishige Ito
Anomerization reaction of pyranosides with 2,3-trans carbamate group
16th European Carbohydrate Symposium, Sorrent,Italy, 2011.7.3-7
  
S. Dedola, Y. Makimura, M. Izumi, Y. Ito, and Y. Kajihara
Synthesis of homogeneous glycoproteins bearing high-mannose or complex type biantennary asialooligosaccharide
16th European Carbohydrate Symposium, Sorrent,Italy, 2011.7.3-7
  
2010
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
Yukishige Ito
Synthesis of eukaryotic and bacterial glycoprotein glycans
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), Hawaii,USA, 2010.12.15-20
Osamu Kanie
Synthesis and intracellular localization analysis of a fluorescently tagged C-3” fluorinated CMP sialic acid analogue
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), Hawaii,USA, 2010.12.15-20
Y. Takeda, I. Matsuo, K. Totani, Y. Ito
Thermodynamic studies on the interaction between high-mannose-type glycan and malectin
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), Hawaii,USA, 2010.12.15-20
Akihiro Ishiwata, Ayaka Sakurai, Katharina Durr, Yukishige Ito
Accelerated glycosylation under frozen conditions: Effect on stereoselectivity and velocity of O-glycosylation
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), Hawaii,USA, 2010.12.15-20
Akihiro Ishiwata, Yukishige Ito
Synthetic study of mycobacterial arabinan
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), Hawaii,USA, 2010.12.15-20
Kiichiro Totani, Shogo Iwamoto, Hikaru Matsushima, Shogo Isoyama, Yukishige Ito
Top-down and bottom-up approaches to understanding glycan processing in the ER
International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), Hawaii,USA, 2010.12.15-20
Suzuki, K.
CMP-3”-Fluorinated Sialic Acid Derivative for Histochemical Analysis of Subcellular Organella
The 5th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-5), Hsinchu,Taiwan, 2010.11.7-11
  
Osamu Kanie
Fluorescently tagged CMP-3”-fluorinated sialic acid derivative to probe Golgi architecture
8th iCeMS International Symposium, Kyoto,Japan, 2010.11.9-11
  
The 25th International Carbohydrate Symposium (ICS 2010)
Y.Takeda, I.Matsuo, K.Totani, Y.Ito
Substrate Specificity Analysis of Malectin Using Synthetic High-mannose-type Glycans
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
K. Suzuki, Y. Hasegawa, K. Suzuki, A. Ohtake, Y. Ito, O. Kanie
Probing the Golgi architecture with a fluorescently tagged CMP-3"-fluorinated sialic acid derivative
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
S.Daikoku, A.Ohtake, K.Suzuki, M.Kobayashi, E.Fukusaki, Y.Ito, O.Kanie
Development of nanoLC-FL-QIT-TOF-MS for Elucidation of Glycan Processing Event of Glycolipids
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Y.Shiori, K.Suzuki, S.Daikoku, Y.Ito, O.Kanie
Discrimination of Anomers of Monosaccharide Ions Focused on Dissociation of Sodium Cation
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Yong Joo Lee, Akihiro Ishiwata, Akemi Kubota, Taisuke Watanabe, D Kohda, Yukishige Ito
Synthesis of glycans as donor substrates for bacterial protein glycosylation
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Kiichiro Totani, Atsushi Miyagawa, Yukishige Ito
Magnetic beads-assisted mild enrichment procedure for weak binding lectins
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Atsushi Miyagawa, Kiichiro Totani, Ichiro Matsuo, S. Itoda, H. Yamamura, Yukishige Ito
Synthetic probes for the analysis of UGGT activity-rate enhancing effect of cyclodextrins
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Shino Manabe, Kazuyuki Ishii, Daisuke Hashizume, Hiroyuki Koshino, Yukishige Ito
Endocyclic cleavage of 2,3-trans carbamate carrying pyranosides
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Yoshito Ihara, Shino Manabe, M. Ikezaki, Y. Inai, I.-S. Matsui, Y. Ohta, E. Muroi, Yukishige Ito
C-Mannosylated peptides derived from the thrombospondin type 1 repeat interact with Hsc70 to enhance the signaling in RAW264.7 cells
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Ayaka Sakurai, Katharina Durr, Akihiro Ishiwata, Yukishige Ito
Effects of frozen conditions on stereoselectivity and velocity of O-glycosylation reactions
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  
Akihiro Ishiwata, Yukishige Ito
Synthetic study of mycobacterial arabinan
The 25th International Carbohydrate Symposium (ICS 2010), Chiba,Japan, 2010.8.1-6
  

Japan Science and Technology Agency (JST)
ERATO Ito Glycotrilogy Project


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