Education and Experience

Education 1996 Tokyo Institute of Technology (Ph.D.) Experience 1996-1997 Meiji Institute of Health Science, Meiji Milk Products Co. Ltd. (PostDoc) 1997-1999 Frontier Research Program, Institute of Physical and Chemical Research (RIKEN) (PostDoc) 1999-2005 Assistant Prof. of Iwaki Meisei Univ. 2005-2010 Researcher of Mitsubishi Kagaku Inst. Life Sci. 2010- Researcher of ERATO (JST) at RIKEN.

Research Fields

Functional Molecules, Enzymes, Chemical Probes, and Structural Analysis

Recent Publications

Suzuki, K.; Daikoku, S.; Son, S-H.; Ito Y.; Kanie, O. Synthetic study of 3-fluorinated sialic acid derivatives; Carbohydrate Research 406, 1-9 (2015) Son, S-H.; Daikoku, S.; Ohtake, A.; Suzuki, K.; Kabayama, K.; Ito Y.; Kanie, O. Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ; Chem. Commun. 50, 3010–3013 (2014) Shioiri, Y.; Suzuki, K.; Daikoku, S.; Kurimoto, A.; Ito, Y.; Kanie, O. Stereospecific generation and analysis of α- and β-hemiacetals of monosaccharides in gas phase;  Carbohydrate Res. 382, 43–51 (2013). Ohtake, A.; Daikoku, S.; Suzuki, K.; Ito, Y.; Kanie, O. Analysis of the cellular dynamics of fluorescently tagged glycosphingolipids by using a nanoLC-MS/MS platform; Anal. Chem. 85, 8475-8482 (2013) Suzuki, K.; Ohtake, A.: Ito, Y.; Kanie, O. Synthesis of a fluorescently tagged sialic acid analogue useful for live-cell imaging; ChemCommun 48, 9744-9746 (2012). Suzuki, K.; Ito, Y.; Kanie, O. An improved method for the synthesis of protected glycosyl fluorides from thioglycosides using N,N-diethylaminosulfur trifluoride (DAST); Carbohydrate Res. 359, 81-91 (2012). Kanie, O.; Kanie, Y.; Daikoku, S.; Shioiri, Y.; Kurimoto, A.; Mutsuga, S.; Goto, S.; Ito, Y.; Suzuki, K. Multi‐stage mass spectrometric information obtained by deconvolution of energy‐resolved spectra acquired by triplequadrupole mass spectrometry; Rapid Commun. Mass Spectrom. 25, 1617-1624 (2011). Daikoku, S.; Ono, Y.; Ohtake, A.; Hasegawa, Y.; Fukusaki, E.; Suzuki, K.; Ito, Y.; Goto S.; Kanie O. Fluorescence-monitored zero dead-volume nanoLC-microESI-QIT-TOF MS for analysis of fluorescently tagged glycosphingolipids; Analyst 136, 1046-1050 (2011). Suzuki, K.; Tobe, A.; Adachi, S.; Daikoku, S.; Hasegawa, Y.; Shioiri, Y.; Kobayashi, M.; Kanie, O. N-Hexyl-4-aminobutyl glycosides in the structural and biological investigations of oligosaccharide; Org. Biomol. Chem. 7, 4726-4733 (2009). Kanie, O.; Kurimoto, A.; Daikoku, S.; Mutsuga, S.; Kanie, Y.; Suzuki, K. Analysis of behavior of sodiated sugar hemiacetal under low-energy collision dissociation conditions and application to investigating mutarotation and mechanism of a glycosidase; Proc. Jpn Acad. Ser. B. 85, 204-215 (2009). Daikoku, S.; Kurimoto, A.; Mutsuga, S.; Ako, T.; Kanemitsu, T.; Shioiri, Y.; Ohtake, A.; Kato, R.; Saotome, C.; Ohtsuka, I.; Koroghi, S.; Sarkar, S. K.; Tobe, A.; Adachi, S.; Suzuki, K.; Kanie, O. Ion-trap mass spectrometry unvails the presence of isomeric oligosaccharides in an analyte: Stage-discriminated correlation of energy-resolved mass spectrometry; Carbohydr. Res. 343, 384-394 (2009). Shioiri, Y.; Kurimoto, A.; Daikoku, D.; Ishida, H.; Kiso, M.; Suzuki, K.; Kanie, O. Energy-resolved structural details obtained from gangliosides; Anal. Chem. 81, 139-145 (2009). Ono, Y.; Kitajima, M.; Daikoku, S.; Shiroya, T.; Nishihara, S.; Kanie, Y.; Suzuki, K.; Goto, S.; Kanie, O. Sequential enzymatic glycosyltransfer reactions on a microfluidic device: Synthesis of a glycosaminoglycan linkage region tetrasaccharide; Lab. on a Chip.8, 2168-2173 (2008). Shioiri, Y.; Suzuki, K.; Kanie, O. A mechanism of a novel gas-phase reaction via five-membered transition state: Dissociation reaction of 4-aminobutyl glycosides under CID MS/MS conditions; J. Mass Spectrom., 43, 1132-1139.　(2008). Nakahara, T.; Okamoto,N.; Suzuki, K.; Kanie, O. Synthetic study towards a new scaffold, spirobicycloimidazoline; Carbohydrate Res., 343, 1624-1635 (2008). Suzuki, K.; Daikoku, S.; Ako, T.; Kurimoto, A.; Ohtake, A.; Shioiri, Y.; Sarkar, S. K.; Kanie, O. High yielding and controlled dissociation of glycosides producing B- and C-ion species under CID MS/MS conditions and use in structure determination; Aanl. Chem., 79, 9022-9029 (2007).

Presentation

Probing the Golgi Architecture with a Fluorescnetly Tagged CMP-3”-fluorinated Sialic Acid Derivative