“Sequence” or the order of repeating units can be regarded as an essential structural factor for polymers, because functions in natural polymers such as DNA and proteins are totally determined by the sequence. However, there are little methodologies to control sequence for synthetic counterparts. In this research, we propose a strategy to control sequence for vinyl polymers via iterative cyclization, which is realized by design of two kinds of “cleavable but renewable bonds” in molecules for living radical polymerization. Sequence control is expected to contribute to development of functional materials.
JST PRESTO Research Area “Molecular technology and creation of new functions” Research Theme “Creative macromolecular chains via bond manipulation: advanced functions from control of position, sequence, and topology”
Yusuke Hibi, Makoto Ouchi, and Mitsuo Sawamoto. “A strategy for sequence control in vinyl polymers via iterative controlled radical cyclization”. Nature communications, Published online 21 March 2016, doi: 10.1038/ncomms11064.
Makoto Ouchi, Ph.D.
Associate Professor, Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University
Sofia Saori Suzuki
Green Innovation Group, Department of Innovation Research, JST