Siomi Team　　Result

(34) 2012Nishimasu H, Ishizu H, Saito K, Fukuhara S, Kamatani MK, Bonnefond L, Matsumoto N, Nishizawa T, Nakanaga K, Aoki J, Ishitani R, Siomi H, Siomi MC, Nureki O. "Structure and function of Zucchini endoribonuclease in piRNA biogenesis" Nature. 2012 Oct 14. doi: 10.1038/nature11509. [Epub ahead of print]

(33) 2011 Cernilogar FM, Onorati MC, Kothe GO, Burroughs AM, Parsi KM, Breiling A, Sardo FL, Saxena A, Miyoshi K, Siomi H, Siomi MC, Carninci P, Gilmour DS, Corona DFV and Orlando V. Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila. Nature 480: 391-395. 2011

(34) 2011Sato K, Nishida KM, Shibuya A, Siomi MC and Siomi H.?Maelstrom coordinates microtubule organization during Drosophila oogenesis through interaction with components of the MTOC. Genes Dev. 25: 2361-2373. 2011

(35) 2011 Nagao A, Sato K, Nishida KM, Siomi H and Siomi MC. Gender-specific hierarchy in nuage localization of PIWI-interacting RNA factors in Drosophila. Front. Gene. 2: 55. 2011

(32)2010 Miyoshi T, Takeuchi A, Siomi H, Siomi MC.?A direct role for Hsp90 in pre-RISC formation in Drosophila. Nat. Struct. Mol. Biol. 17: 1024-1026. 2010 (doi:10.1038/nsmb.1875?)

(31)2010 Saito K, Ishizu H, Komai H, Kotani H, Kawamura Y, Nishida KM, Siomi H, Siomi MC. Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila. Genes Dev. 24: 2493-2498. 2010 (doi:10.1101/gad.1989510)

(30)2010 Nagao A, Mitsuyama T, Huang H, Chen D, Siomi MC, Siomi H. Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis. RNA 16: 2503-2515.?2010 (doi:10.1261/rna.2270710?)

(29)2010 Miyoshi T, Takeuchi A, Siomi H, Siomi MC."A direct role for Hsp90 in pre-RISC formation in　drosophila." Nat. Struct. Mol. Biol. 17: 1024-1026. 2010

(28)2010 Miyoshi K, Miyoshi T, Hartig J, Siomi H and Siomi MC. Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila. RNA 2010 16: 506-515.

(27)2010 Siomi MC." piRNAs (PIWI-interacting RNA)" McGraw Hill 2010 Yearbook of Science & Technology.

(26)2010 Siomi MC, Miyoshi T, and Siomi H. piRNA-mediated silencing in Drosophila germlines. Seminars in Cell and Developmental Biology 2010 Sep;21(7):754-9. Epub 2010 Jan 18. (review)

(25)2010 Siomi H and Siomi MC. "Posttranscriptional regulation of microRNA biogenesis." Mol. Cell May 14;38(3):323-32. (review)

(24)2009 Siomi MC. JOURNAL CLUB: "A biologist praises a mouse model of autism inheritance "Nature. 2009. 461: 451.

(23)2009 Siomi MC." Short interfering RNA-mediated gene silencing; towards successful application in human patients" Adv. Drug Deliv. Rev. 2009. 61: 668-671. (review)

(22)2009 Siomi H and Siomi MC."RISC hitches onto endosome trafficking." Nat. Cell Biol. 2009. 11: 1049-1051. (review)

(21)2009Siomi MC, Mannen T and Siomi H. "How does the Royal Family of Tudor rule the PIWI-interacting RNA pathway? "Genes Dev. 2010 24: 636-646. (review)

(20)2009 Miyoshi K, Okada T. Siomi H and Siomi MC. "Biochemical analyses of endogenous Argonaute proteins immunopurified from living cells with anti-Argonaute monoclonal antibodies." Methods in Molecular Biology 2011 725 29-43.

(19)2009 Miyoshi K, Okada TN, Siomi H and Siomi MC. "Characterization of miRNA-RISC loading complex and miRNA-RISC formed in Drosophila miRNA pathway." RNA 2009. 15: 1282-1291.

(18)2009 Saito K, Inagaki S, Mituyama T, Kawamura Y, Ono Y, Sakota E, Kotani H, Asai K, Siomi H and Siomi MC."A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila." Nature. 2009. 461: 1296-1301.

(17)2009 Nishida KM, Okada TN, Kawamura T, Mituyama T, Kawamura Y, Inagaki S, Huang H, Chen D, Kodama T, Siomi H and Siomi MC. "Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. "EMBO J. 2009. 28: 3820-3831

(16) May 23.2009Dr.MC Siomi was awarded the 29th (FY 2009) Saruhashi Prize .

(15) 2009Saito K, Mituyama T, Inagaki S, Ono Y, Sakota E, Asai K, Siomi H, and Siomi MC. The primary processing pathway produces piRNAs and meRNAs for Piwi in Drosophila ovarian somas.

(14) 2009Miyoshi K, Okada TN, Siomi H, Siomi MC. Characterization of miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway.

(13) Oct.25 2008"Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing"at the 20th FAOBMB Taipei Conference Frontier in Life Sciences.

(12) Oct.23 2008Invitation Lecture:""Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing"at the Academia SINICA（Taipei）

(11) Jul.15 2008Invitation Lecture:" Drosophila endogenous small RNAs bind to Argonaute2 in somatic cells" on the Symposium"RNA machine"at the 20th International Congress of Genetics,Germany.

(10) May.7 2008Invitation Lecture:"Drosophila endogenous small RNAs bind to Argonaute2 in somatic cells" at the Seoul Univ.,Korea.

(9) 2008Siomi MC, Kuramochi-Miyagawa S. RNA Silencing in germlines - exquisite collaboration of Argonautes with small RNAs for germline survival. Current Opinion in Cell Biology.

(8) 2008Kim NV, Han J, Siomi M.C. Biogenesis of small RNAs in animals. Nature Reviews Molecular Cell Biology,vol.10 p127-139,Feb.2009

(7) 2008Siomi, H., Siomi, MC. On the road to reading the RNA interference code. Nature, vol.457 p396-404,22 Jan.2009

(6) 2008 Siomi MC, Nishida KM, Siomi H.?How to defining RNAi targets.?Methods in Enzymology vol. 449 (2008)

(5) 2008Siomi MC, Saito K, Siomi H.? How selfish retorotransposons are silenced in Drosophila germline and somatic cells ?FEBS Lett. 582: 2473-2478 (2008)

(4) 2008Y. Kawamura, K. Saito, T. Kin, Y. Ono, K. Asai, T. Sunohara, T.N. Okada, M.C. Siomi* and H. Siomi. "Drosophila endogenous small RNAs bind to Argonaute2 in somatic cells." Nature 453: 793-797. 2008 (*correspondences)

(3) 2008A.M. Azuma, H. Oguri, T. Kin, Z.R. Qian, K. Asai, H. Siomi and M.C. Siomi. "Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing." PNAS 105(23):7964-9

(2) Sep.13 2007M. Nishida, K. Saito, T. Mori, Y. Kawamura, T.N. Okada, S. Inagaki, H. Siomi and M.C. Siomi. "Gene silencing mechanisms mediated by Aubergine piRNA complexes in Drosophila male gonad." RNA 13:1911-1922. 2007; Epub Sep 13 2007.

(1) Oct. 2 2007Mikiko Siomi gave the invitation lecture on "RNA silencing in Drosophila germlines" at the 23rd Ernst Klenk Symposium in Molecular Medicine "Non-coding RNA"(Scientific Organizer: Dr. Tom Tuschl） in Cologne,Germany.