SICP: Strategic International Research Cooperative Program / SICORP: Strategic International Collaborative Research Program



JST-ETHZ workshop on Molecular Medical Research
22.-24.09.2009 in Tokyo At Izumi Garden Conference Centre. Tokyo, Japan


JST-ETHZ workshop on Molecular Medical Research

Organizers :
Takehiko Sasazuki, M.D., Ph.D, President Emeritus, International Medical Center of Japan
Georg Andreas Peter Holländer, M.D., Ph.D, Professor, Basel University Children's Hospital and University of Basel

22nd, September
Opening Remarks
  9:30-  9:40  Akira Takamatsu, Executive Director, JST
  9:40-  9:50  Rahel Byland, Representaive from ETHZ
  9:50-10:00  Takehiko Sasazuki, International Medical Center of Japan
10:00-10:10  Georg Andreas Peter Holländer, Basel University Children's Hospital

Session 1 : Pharmacogenomics and Drug Discovery
10:15-10:45  "Pharmacogenomics for Rheumatic Diseases"
By Naoyuki Kamatani, Team Leader, Laboratory for Statistical Analysis, RIKEN
Abstract: Naoyuki Kamatani 
10:45-11:15  "Plasticity of protein structures as challenge for structure-based drug discovery"
By Markus Grütter, Head Department of Biochemistry, University of Zurich
Abstract: Markus Grütter 
11:15-11:30  Coffee Break
11:30-12:00  "Pharmaco- and immunogenomics upon HIV-1 infection"
By Shinichi Oka, Director-General, AIDS Clinical Center (ACC), International Medical Center of Japan
Abstract: Shinichi Oka 
12:00-12:30  "Identification of cellular mechanisms required for the recovery from DNA replication fork arrest"
By Kenji Shimada, Research Associate, Friedrich Miescher Institute Basel
Abstract: Kenji Shimada 
12:30-13:30  Lunch Break

Session 2 : Bioinformatics
13:30-14:00  "Systems Drug Discovery"
By Hiroaki Kitano, Director, The System Biology Institute
Abstract: Hiroaki Kitano 
14:00-14:30  "Evolution towards disease: combating a moving target"
By Niko Beerenwinkel, Professor, Computational Biology Group, ETH Department of Biosystems Science and Engineering, Basel
Abstract: Niko Beerenwinkel 
14:30-15:00  "Human Genome Network"
By Takashi Gojobori, Vice Director, National Institute of Genetics
Abstract: Takashi Gojobori 
15:00-15:30  "Structure based rational design of new inhibitors for cancer therapy"
By Olivier Michielin, Professor, Molecular Modelling, Swiss Institute for Bioinformatics, Lausanne
Abstract: Olivier Michielin 
15:30-15:45  Coffee Break

Session 3 :Translational Research
15:45-16:15  "Molecular and cellular aspects in thymus organogenesis and function"
By Georg Andreas Peter Holländer, Professor, Basel University Children's Hospital and University of Basel
16:15-16:45  "Interferon signaling in chronic viral hepatitis"
By Markus Heim, Professor in Hepatology, Department of Biomedicine, University Hospital and University of Basel
Abstract: Markus Heim 
16:45-17:15  "Discovery and clinical application of a novel oncogene, EML4-ALK, in lung cancer"
By Hiroyuki Mano, Jichi Medical University
Abstract: Hiroyuki Mano 
17:15-17:45  "The role of mTOR signaling in the regulation of size in normal and diseased muscle"
By Markus Rüegg, Professor of Neurobiology, Biozentrum, Basel
Abstract: Markus Rüegg 
17:45  End of Session

23rd, September
Session 4 : Proteomics and Development of Biomarker
10:00-10:30  "Cancer Biomarker and Drug Target Discovery by Proteomics"
By Tesshi Yamada, Chief, Chemotherapy Division, National Cancer Center
Abstract: Tesshi Yamada 
10:30-11:00  "Phenotyping cells without antibodies: mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins"
By Bernd Wollscheid, Group Leader Institute of Molecular Systems Biology, ETH Zurich
Abstract: Bernd Wollscheid 
11:00-11:30  "Clinical Proteomics in Hepatobiliary Diseases -From Bench to Practice-"
By Fumio Nomura, Professor, Chiba University
Abstract: Fumio Nomura 
11:30-12:00  "Annotation of human proteins in the context of molecular medicine: current status and future developments"
By Amos Bairoch, Director and Professor, Department of Structural Biology and Bioinformatics, Faculty of Medicine, University of Geneva. Group Leader, Swiss Institute of Bioinformatics
Abstract: Amos Bairoch 
12:00-13:00  Lunch Break
Session 5 : Genes and Gene Networks Involved in Disease
13:00-13:30  "Exploring genetic basis of GVHD through whole genome association studies"
By Seishi Ogawa, Associate Professor, The University of Tokyo Hospital
Abstract: Seishi Ogawa 
13:30-14:00  "The power of mouse genetic referent populations for the identification of polygenic gene-phenotype networks"
By Xavier Warot, Group Leader Center of Phenogenomics, EPF Lausanne
Abstract: Xavier Warot 
14:00-14:30  "HLA and non HLA genes involved in autoimmune thyroid diseases"
By Takehiko Sasazuki, President Emeritus, International Medical Center of Japan
Abstract: Takehiko Sasazuki 
14:30-15:00  "Mapping gene regulatory networks to understand transcription factor function in health and disease"
By Bart Deplancke, Professor, Systems Biology and Genetics, EPF Lausanne
Abstract: Bart Deplancke 
15:00-15:15  Coffee Break
Session for Discussion
15:15-16:00  Chair: Takehiko Sasazuki and Georg Andreas Peter Holländer
Closing Remarks
16:00-16:10  Takehiko Sasazuki, International Medical Center of Japan
16:10-16:20  Georg Andreas Peter Holländer, Basel University Children's Hospital
16:20  End of Program

24th, September
Technical Tour : RIKEN Yokohama Laboratory




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