本文
Organizations :
Japan Science and Technology Agency (JST)
Swiss Federal Institute of Technology Zurich (ETHZ)
Japan Science and Technology Agency (JST)
Swiss Federal Institute of Technology Zurich (ETHZ)
Organizers :
Takehiko Sasazuki, M.D., Ph.D, President Emeritus, International Medical Center of Japan
Georg Andreas Peter Holländer, M.D., Ph.D, Professor, Basel University Children's Hospital and University of Basel
Takehiko Sasazuki, M.D., Ph.D, President Emeritus, International Medical Center of Japan
Georg Andreas Peter Holländer, M.D., Ph.D, Professor, Basel University Children's Hospital and University of Basel
22nd, September
Opening Remarks
9:30- 9:40 Akira Takamatsu, Executive Director, JST
9:40- 9:50 Rahel Byland, Representaive from ETHZ
9:50-10:00 Takehiko Sasazuki, International Medical Center of Japan
10:00-10:10 Georg Andreas Peter Holländer, Basel University Children's Hospital
Session 1 : Pharmacogenomics and Drug Discovery
10:15-10:45 "Pharmacogenomics for Rheumatic Diseases"
By Naoyuki Kamatani, Team Leader, Laboratory for Statistical Analysis, RIKEN
By Naoyuki Kamatani, Team Leader, Laboratory for Statistical Analysis, RIKEN
10:45-11:15 "Plasticity of protein structures as challenge for structure-based drug discovery"
By Markus Grütter, Head Department of Biochemistry, University of Zurich
By Markus Grütter, Head Department of Biochemistry, University of Zurich
11:15-11:30 Coffee Break
11:30-12:00 "Pharmaco- and immunogenomics upon HIV-1 infection"
By Shinichi Oka, Director-General, AIDS Clinical Center (ACC), International Medical Center of Japan
By Shinichi Oka, Director-General, AIDS Clinical Center (ACC), International Medical Center of Japan
12:00-12:30 "Identification of cellular mechanisms required for the recovery from DNA replication fork arrest"
By Kenji Shimada, Research Associate, Friedrich Miescher Institute Basel
By Kenji Shimada, Research Associate, Friedrich Miescher Institute Basel
12:30-13:30 Lunch Break
Session 2 : Bioinformatics
13:30-14:00 "Systems Drug Discovery"
By Hiroaki Kitano, Director, The System Biology Institute
By Hiroaki Kitano, Director, The System Biology Institute
14:00-14:30 "Evolution towards disease: combating a moving target"
By Niko Beerenwinkel, Professor, Computational Biology Group, ETH Department of Biosystems Science and Engineering, Basel
By Niko Beerenwinkel, Professor, Computational Biology Group, ETH Department of Biosystems Science and Engineering, Basel
14:30-15:00 "Human Genome Network"
By Takashi Gojobori, Vice Director, National Institute of Genetics
By Takashi Gojobori, Vice Director, National Institute of Genetics
15:00-15:30 "Structure based rational design of new inhibitors for cancer therapy"
By Olivier Michielin, Professor, Molecular Modelling, Swiss Institute for Bioinformatics, Lausanne
By Olivier Michielin, Professor, Molecular Modelling, Swiss Institute for Bioinformatics, Lausanne
15:30-15:45 Coffee Break
Session 3 :Translational Research
15:45-16:15 "Molecular and cellular aspects in thymus organogenesis and function"
By Georg Andreas Peter Holländer, Professor, Basel University Children's Hospital and University of Basel
By Georg Andreas Peter Holländer, Professor, Basel University Children's Hospital and University of Basel
16:15-16:45 "Interferon signaling in chronic viral hepatitis"
By Markus Heim, Professor in Hepatology, Department of Biomedicine, University Hospital and University of Basel
By Markus Heim, Professor in Hepatology, Department of Biomedicine, University Hospital and University of Basel
16:45-17:15 "Discovery and clinical application of a novel oncogene, EML4-ALK, in lung cancer"
By Hiroyuki Mano, Jichi Medical University
By Hiroyuki Mano, Jichi Medical University
17:15-17:45 "The role of mTOR signaling in the regulation of size in normal and diseased muscle"
By Markus Rüegg, Professor of Neurobiology, Biozentrum, Basel
By Markus Rüegg, Professor of Neurobiology, Biozentrum, Basel
17:45 End of Session
23rd, September
Session 4 : Proteomics and Development of Biomarker
10:00-10:30 "Cancer Biomarker and Drug Target Discovery by Proteomics"
By Tesshi Yamada, Chief, Chemotherapy Division, National Cancer Center
By Tesshi Yamada, Chief, Chemotherapy Division, National Cancer Center
10:30-11:00 "Phenotyping cells without antibodies: mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins"
By Bernd Wollscheid, Group Leader Institute of Molecular Systems Biology, ETH Zurich
By Bernd Wollscheid, Group Leader Institute of Molecular Systems Biology, ETH Zurich
11:00-11:30 "Clinical Proteomics in Hepatobiliary Diseases -From Bench to Practice-"
By Fumio Nomura, Professor, Chiba University
By Fumio Nomura, Professor, Chiba University
11:30-12:00 "Annotation of human proteins in the context of molecular medicine: current status and future developments"
By Amos Bairoch, Director and Professor, Department of Structural Biology and Bioinformatics, Faculty of Medicine, University of Geneva. Group Leader, Swiss Institute of Bioinformatics
By Amos Bairoch, Director and Professor, Department of Structural Biology and Bioinformatics, Faculty of Medicine, University of Geneva. Group Leader, Swiss Institute of Bioinformatics
12:00-13:00 Lunch Break
Session 5 : Genes and Gene Networks Involved in Disease
13:00-13:30 "Exploring genetic basis of GVHD through whole genome association studies"
By Seishi Ogawa, Associate Professor, The University of Tokyo Hospital
By Seishi Ogawa, Associate Professor, The University of Tokyo Hospital
13:30-14:00 "The power of mouse genetic referent populations for the identification of polygenic gene-phenotype networks"
By Xavier Warot, Group Leader Center of Phenogenomics, EPF Lausanne
By Xavier Warot, Group Leader Center of Phenogenomics, EPF Lausanne
14:00-14:30 "HLA and non HLA genes involved in autoimmune thyroid diseases"
By Takehiko Sasazuki, President Emeritus, International Medical Center of Japan
By Takehiko Sasazuki, President Emeritus, International Medical Center of Japan
14:30-15:00 "Mapping gene regulatory networks to understand transcription factor function in health and disease"
By Bart Deplancke, Professor, Systems Biology and Genetics, EPF Lausanne
By Bart Deplancke, Professor, Systems Biology and Genetics, EPF Lausanne
15:00-15:15 Coffee Break
Session for Discussion
15:15-16:00 Chair: Takehiko Sasazuki and Georg Andreas Peter Holländer
Closing Remarks
16:00-16:10 Takehiko Sasazuki, International Medical Center of Japan
16:10-16:20 Georg Andreas Peter Holländer, Basel University Children's Hospital
16:20 End of Program
24th, September
Technical Tour : RIKEN Yokohama Laboratory
