Nakatsu S, Murakami S, Shindo K, Horimoto T, Sagara H, Noda T, Kawaoka Y.
Influenza C and D viruses package eight organized ribonucleoprotein complexes.
J Virol. 2018 Jan 10. pii: JVI.02084-17.
Noda T, Murakami S, Nakatsu S, Imai H, Muramoto Y, Shindo K, Sagara H, Kawaoka Y.
Importance of the 1+7 configuration of ribonucleoprotein complexes for influenza A virus genome packaging.
Nat Commun. 2018 Jan 4;9(1):54.
Wan W, Kolesnikova L, Clarke M, Koehler A, Noda T, Becker S, Briggs JAG.
Structure and assembly of the Ebola virus nucleocapsid.
Nature. 2017 Nov 16;551(7680):394-397.
Oda S, Noda T, Wijesinghe KJ, Halfmann P, Bornholdt ZA, Abelson DM, Armbrust T, Stahelin RV, Kawaoka Y, Saphire EO. Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression. J Virol. 2015 Dec 9;90(4):1839-48. doi: 10.1128/JVI.01597-15.
Koga R, Sugita Y, Noda T, Yanagi Y, Ohno S. Actin-Modulating Protein Cofilin Is Involved in the Formation of Measles Virus Ribonucleoprotein Complex at the Perinuclear Region. J Virol. 2015 Oct;89(20):10524-31. doi: 10.1128/JVI.01819-15. Epub 2015 Aug 12.
Watanabe T, Kawakami E, Shoemaker JE, Lopes TJ, Matsuoka Y, Tomita Y, Kozuka-Hata H, Gorai T, Kuwahara T, Takeda E, Nagata A, Takano R, Kiso M, Yamashita M, Sakai-Tagawa Y, Katsura H, Nonaka N, Fujii H, Fujii K, Sugita Y, Noda T, Goto H, Fukuyama S, Watanabe S, Neumann G, Oyama M, Kitano H, Kawaoka Y. Influenza virus-host interactome screen as a platform for antiviral drug development. Cell Host Microbe. 2014 Dec 10;16(6):795-805. doi: 10.1016/j.chom.2014.11.002. Epub 2014 Nov 20
Hatakeyama D, Shoji M, Yamayoshi S, Hirota T, Nagae M, Yanagisawa S, Nakano M, Ohmi N, Noda T, Kawaoka Y, Kuzuhara T. A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication. J Biol Chem. 2014 Sep 5;289(36):24980-94. doi: 10.1074/jbc.M114.559708. Epub 2014 Jul 25
Muramoto Y, Shoemaker JE, Le MQ, Itoh Y, Tamura D, Sakai-Tagawa Y, Imai H, Uraki R, Takano R, Kawakami E, Ito M, Okamoto K, Ishigaki H, Mimuro H, Sasakawa C, Matsuoka Y, Noda T, Fukuyama S, Ogasawara K, Kitano H, Kawaoka Y. Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza viruses. J Virol. 2014 Aug;88(16):8981-97. doi: 10.1128/JVI.00907-14. Epub 2014 Jun 4.
Liu Z, Kato A, Shindo K, Noda T, Sagara H, Kawaoka Y, Arii J, Kawaguchi Y. Herpes simplex virus 1 UL47 interacts with viral nuclear egress factors UL31, UL34, and Us3 and regulates viral nuclear egress. J Virol. 2014 May;88(9):4657-67. doi: 10.1128/JVI.00137-14. Epub 2014 Feb 1
Bornholdt ZA, Noda T, Abelson DM, Halfmann P, Wood MR, Kawaoka Y, Saphire EO. Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle. Cell. 154:763-74 (2013)
Sugita Y, Sagara H, Noda T*, Kawaoka Y*. The configuration of viral ribonucleoprotein complexes within the influenza A virion. J Virol. 87: 12879-84 (2013)
Goto H, Muramoto Y, Noda T, Kawaoka Y. The genome-packaging signal of the influenza a virus genome comprises a genome incorporation signal and a genome-bundling signal. J Virol. 87:11316-22 (2013)
Watanabe T, Kiso M, Fukuyama S, Nakajima N, Imai M, Yamada S, Murakami S, Yamayoshi S, Iwatsuki-Horimoto K, Sakoda Y, Takashita E, McBride R, Noda T, Hatta M, Imai H, Zhao D, Kishida N, Shirakura M, de Vries RP, Shichinohe S, Okamatsu M, Tamura T, Tomita Y, Fujimoto N, Goto K, Katsura H, Kawakami E, Ishikawa I, Watanabe S, Ito M, Sakai-Tagawa Y, Sugita Y, Uraki R, Yamaji R, Eisfeld AJ, Zhong G, Fan S, Ping J, Maher EA, Hanson A, Uchida Y, Saito T, Ozawa M, Neumann G, Kida H, Odagiri T, Paulson JC, Hasegawa H, Tashiro M, Kawaoka Y. Characterization of H7N9 influenza A viruses isolated from humans. Nature. 501:551-5 (2013)
Takahashi K, Halfmann P, Oyama M, Kozuka-Hata H, Noda T*, Kawaoka Y*. DNA topoisomerase 1 facilitates the transcription and replication of the Ebola virus genome. J Virol. 87:8862-9 (2013)
Fehling SK, Noda T, Maisner A, Lamp B, Conzelmann KK, Kawaoka Y, Klenk HD, Garten W, Strecker T. The microtubule motor protein KIF13A is involved in intracellular trafficking of the Lassa virus matrix protein Z. Cell Microbiol 15;315-34 (2013)
Muramoto Y, Noda T, Kawakami E, Akkina R, Kawaoka Y. Identification of novel influenza A virus proteins translated from PA mRNA. J Virol 87;2455-62. (2013)
Haraguchi H, Noda T, Kawaoka Y, Morikawa Y. HIV-1 A large extension to HIV-1 Gag, like Pol, has negative impacts on virion assembly. PLoS One, e47828 (2012).
Kajihara M, Marzi A, Nakayama E, Noda T, Kuroda M, Manzoor R, Matsuno K, Feldmann H, Yoshida R, Kawaoka Y, Takada A. Inhibition of Marburg virus budding by nonneutralizing antibodies to the envelope glycoprotein. J. Virol., 86;13467-74 (2012)
Noda T*, Kawaoka Y*. Packaging of influenza virus genome; Robustness of selection. Proc. Natl. Acad. Sci. USA, 109; 8797-8. (2012)
Shinya K, Gao Y, Cilloniz C, Suzuki Y, Fujie M, Deng G, Zhu Q, Fan S, Makino A, Muramoto Y, Fukuyama S, Tamura D, Noda T, Eisfeld AJ, Katze MG, Chen H, Kawaoka Y. Integrated clinical, pathologic, virologic, and transcriptomic analysis of H5N1 influenza virus-Induced viral pneumonia in the Rhesus Macaque. J. Virol.86: 6055-66. (2012)
Bharat T, Noda T, Riches JD, Krahling V, Kolesnikova L, Becker S, Kawaoka Y, Briggs J. Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography. Proc. Natl. Acad. Sci. USA 109: 4275-80. (2012)
Gorai T, Goto H, Noda T, Watanabe T, Kozuka-Hata H, Oyama M, Takano R, Neumann G, Watanabe S, Kawaoka Y. The F1F0-ATPase at the plasma membrane is critical for efficient influenza virus budding. Proc. Natl. Acad. Sci. USA 109: 4615-20. (2012)
Noda T*, Sugita Y, Aoyama K, Hirase A, Kawakami E, Miyazawa A, Sagara H, Kawaoka Y*. Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus. Nature Communications. 3; 639 (2012).
Das SC, Watanabe S, Hatta M, Noda T, Neumann G, Ozawa M, Kawaoka Y. The arginine residues at positions 76-78 of influenza A virus matrix protein M1 play an important role in viral replication. J. Virol. 86; 1522-30 (2012).
Sugita Y, Noda T*, Sagara H, Kawaoka Y*. Ultracentrifugation deforms unfixed influenza A virions. J. Gen. Virol. 92: 2458-93 (2011).
Noda T, Kolesnikova L, Becker S, Kawaoka Y. The importance of the NP:VP35 ratio in Ebola virus nucleocapsid formation. J. Infect. Dis., Sup3: S878-83 (2011).
Makino A, Yamayoshi S, Shinya K, Noda T, Kawaoka Y. Identification of amino acids in Marburg virus VP40 that are important for virus-like particle budding. J. Infect. Dis., Sup3: S871-7 (2011)
Iwasa A, Halfmann P, Noda T, Oyama M, Kozuka-Hata H, Watanabe S, Shimojima M, Watanabe T, Kawaoka Y. Contribution of Sec61a to the life cycle of Ebola virus. J. Infect. Dis. Sup3: S919-26 (2011).
Kiso M, Ozawa M, Le MT, Imai H, Takahashi K, Kakugawa S, Noda T, Horimoto T, Kawaoka Y. Effect of an asparagines-to-serine mutation at position 294 in neuraminidase on the pathogenicity of highly pathogenic H5N1 influenza A virus. J. Virol., 85: 4667-72 (2011).
Octaviani CP, Li C, Noda T, Kawaoka Y. Reassortment between seasonal and swine-origin H1N1 influenza viruses generates viruses with enhanced growth capability in cell culture. Virus Res., 156: 147-50 (2011).
Furukawa T, Muraki Y, Noda T, Takashita E, Sho R, Sugawara K, Matsuzaki Y, Shimotai Y, Hongo S. Role of the CM2 protein in the influenza C virus replication cycle. J. Virol., 85: 1322-9 (2011).
Kawakami E, Watanabe T, Fujii K, Goto H, Watanabe S, Noda T, Kawaoka Y. Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA. J. Virol. Methods, 173: 1-6 (2011).
Tomita Y, Noda T, Fujii K, Watanabe T, Morikawa Y, Kawaoka Y. The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles. J. Virol. 85: 5618-27 (2011).
Akarsu H, Iwatsuki-Horimoto K, Noda T, Kawakami E, Katsura H, Baudin F, Horimoto T, Kawaoka Y. Structure-based design of NS2 mutants for attenuated influenza A virus vaccines. Virus Res., 155: 240-8 (2011).
Haraguchi H, Sudo S, Noda T, Momose F, Kawaoka Y, Morikawa Y. Intracellular localization of human immunodeficiency virus type 1 Gag and GagPol products and virus particle release: relationship with the Gag-to-GagPol ratio. Microbiol. Immunol., 54: 734-46 (2010).
Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, Halfmann P, Kawaoka Y. Ebolavirus is internalized into host cells via Macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog., 6: e1001121 (2010).
Imai H, Shinya K, Takano R, Kiso M, Muramoto Y, Sakabe S, Murakami S, Ito M, Yamada S, Le MT, Nidom CA, Sakai-Tagawa Y, Takahashi K, Omori Y, Noda T, Shimojima M, Kakugawa S, Goto H, Iwatsuki-Horimoto K, Horimoto T, Kawaoka Y. The HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets. PLoS Pathog., 6: e1001106 (2010).
Noda T, Hagiwara K, Sagara H, Kawaoka Y. Characterization of the Ebola virus nucleoprotein-RNA complex. J. Gen. Virol., 91: 1478-83 (2010).
Noda T*, Kawaoka Y*. Structure of influenza virus ribonucleoprotein complexes and their packaging into virions. Rev. Med. Virol., 20: 380-91 (2010).
Neumann G, Noda T, Kawaoka Y. Emergence and pandemic potential of swine-origin H1N1 influenza virus. Nature 459: 931-939 (2009).
Itoh Y, Shinya K, Kiso M, Watanabe T, Sakoda Y, Hatta M, Muramoto Y, Tamura D, Sakai-Tagawa Y, Noda T, Sakabe S, Imai M, Hatta Y, Watanabe S, Li C, Yamada S, Fujii K, Murakami S, Imai H, Kakugawa S, Ito M, Takano R, Iwatsuki-Horimoto K, Shimojima M, Horimoto T, Goto H, Takahashi K, Makino A, Ishigaki H, Nakayama M, Okamatsu M, Takahashi K, Warshauer D, Shult PA, Saito R, Suzuki H, Furuta Y, Yamashita M, Mitamura K, Nakano K, Nakamura M, Brockman-Schneider R, Mitamura H, Yamazaki M, Sugaya N, Suresh M, Ozawa M, Neumann G, Gern J, Kida H, Ogasawara K, Kawaoka Y. In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature 46: 1021-1025 (2009).
Sakuma T, Noda T, Urata S, Kawaoka Y, Yasuda J. Inhibition of Lassa and Marburg virus production by tetherin. J. Virol. 83: 2382-2385 (2009).
Yamayoshi S, Noda T, Ebihara H, Goto H, Morikawa Y, Lukashevich IS, Neumann G, Feldmann H, Kawaoka Y. Ebola Virus Matrix VP40 Protein Uses the COPII Transport System for Its Intracellular Transport. Cell host Microbe. 3: 168-177 (2008).
Halfmann P, Kim JH, Ebihara H, Noda T, Neumann G, Feldmann H, Kawaoka Y. Generation of biologically contained Ebola viruses. Proc. Natl. Acad. Sci. USA 105: 1129-1133 (2008).
Noda T, Halfmann P, Sagara H, Kawaoka Y. Regions in Ebola virus VP24 that are important for nucleocapsid formation. J. Infect. Dis. 196 Suppl 2: S247-250 (2007).
Watanabe S, Noda T, Halfmann P, Jasenosky L, Kawaoka Y. Ebola virus (EBOV) VP24 inhibits transcription and replication of the EBOV genome. J. Infect. Dis. 196 Suppl 2: S284-290 (2007).
Urata S, Noda T, Kawaoka Y, Morikawa S, Yokosawa H, Yasuda J. Interaction of Tsg101 with Marburg virus VP40 depends on the PPPY motif, but not the PT/SAP motif as in the case of Ebola virus, and Tsg101 plays a critical role in the budding of Marburg virus-like particles induced by VP40, NP, and GP. J. Virol. 81: 4895-4899 (2007).
Noda T, Watanabe S, Sagara H, Kawaoka Y. Mapping of the VP40-binding regions of the nucleoprotein of Ebola virus. J. Virol. 81: 3554-3562 (2007).
Noda T, Ebihara H, Muramoto Y, Fujii K, Takada A, Sagara H, Kim JH, Kida H, Feldmann H, Kawaoka Y. Assembly and budding of Ebolavirus. PLoS Pathog. 2: e99 (2006).
Iwatsuki-Horimoto K, Horimoto T, Noda T, Kiso M, Maeda J, Watanabe S, Muramoto Y, Fujii K, Kawaoka Y. The cytoplasmic tail of the influenza A virus M2 protein plays a role in viral assembly. J. Virol. 80: 5233-5240 (2006).
Urata S, Noda T, Kawaoka Y, Yokosawa H, Yasuda J. Cellular factors required for Lassa virus budding. J. Virol. 80: 4191-4195 (2006).
Watanabe S, Noda T, Kawaoka Y. Functional mapping of the nucleoprotein of Ebola virus. J. Virol. 80: 3743-3751 (2006).
Noda T, Sagara H, Yen A, Takada A, Kida H, Cheng H, Kawaoka Y. Architecture of ribonucleoprotein complexes in influenza A virus particles. Nature 439: 490-492 (2006).
Muramoto Y, Takada A, Fujii K, Noda T, Iwatsuki-horimoto K, Watanabe S, Horimoto T, Kida H, Kawaoka Y. Hierarchy among vRNA segments in their role in vRNA incorporation into influenza A virions J. Virol. 80: 2318-2325 (2006).
Neumann G, Ebihara H, Takada A, Noda T, Kobasa D, Jasenosky LD, Watanabe S, Kim JH, Accola MA, Feldmann H, Kawaoka Y. The Ebola virus VP40 late domains are not essential for viral replication in cell culture. J. Virol. 79: 10300-10307 (2005).
Noda T, Aoyama K, Sagara H, Kida H, Kawaoka Y. Nucleocapsid-like structures of Ebola virus reconstructed using electron tomography. J. Vet. Med. Sci. 67: 325-328 (2005).
Fujii K, Fujii Y, Noda T, Muramoto Y, Watanabe T, Takada A, Goto H, Horimoto T, Kawaoka Y. Importance of both the coding and the segment-specific noncoding regions of the influenza A virus NS segment for its efficient incorporation into virions. J. Virol. 79: 3766-3774 (2005).
Watanabe S, Watanabe T, Noda T, Takada A, Feldmann H, Jasenosky LD, Kawaoka Y. Production of novel Ebola virus-like particles from cDNAs: an alternative to Ebola virus generation by reverse genetics. J. Virol. 78: 999-1005 (2004).
Noda T, Muramoto Y., Sagara H., Aoyama K., Takada A., Feldmann H., Kida H., Kawaoka Y. Formation of nucleocapsid-like structures of Ebola virus. Proceedings of the 8th Asia-Pacific Conference on Electron microscopy, 1036-1037 (2004).
Watanabe T, Watanabe S, Noda T, Fujii Y, Kawaoka Y. Exploitation of nucleic acid packaging signals to generate a novel influenza virus-based vector stably expressing two foreign genes. J. Virol. 77: 10575-10583 (2003).
Noda T, Sagara H, Suzuki E, Takada A, Kida H, *Kawaoka Y. Ebola virus VP40 drives the formation of virus-like filamentous particles along with GP. J. Virol. 76: 4855-4865 (2002).
