| Name |
Douglas A. Melton |
| Address |
Howard Hughes Medical Institute
Department of Molecular and Cellular Biology
Harvard University
Cambridge, MA 02138
U.S.A. |
| University Education |
|
| 1971-1975 |
B.S. in Honors Biology
University of Illinois, Champaign-Urbana, Illinois |
| 1975-1977 |
B.S. in Honors Biology
University of Illinois, Champaign-Urbana, Illinois |
| 1980 |
Ph.D. in Molecular Biology Trinity College & MRC Laboratory of Molecular Biology
Supervisor: J.B. Gurdon Cambridge University, England |
|
| Scientific Positions |
|
| 1999-Present |
Thomas Dudley Cabot Professor in the Natural Sciences, Harvard University |
| 1994-Present |
Howard Hughes Medical Institute, Investigator |
| 1994-Present |
Associate Member, Children's Hospital Boston |
| 1993-Present |
Biologist (Medicine), Massachusetts General Hospital |
| 1988-Present |
Professor of Molecular and Cellular Biology, Harvard University |
| 1987-1988 |
John L. Loeb Associate Professor of the Natural Sciences, Harvard University |
| 1984-1987 |
Associate Professor, Department of Biochemistry and Molecular Biology, Harvard University |
| 1981-1984 |
Assistant Professor, Department of Biochemistry and Molecular Biology, Harvard University |
|
| Academic Honors |
|
| ・ |
Edmund J. James Scholar, University of Illinois, 1971-1975; Phi Beta Kappa, 1975 |
| ・ |
Marshall Scholarship, awarded for study at Cambridge University, 1975-1978 |
| ・ |
Max Perutz Prize, 1981 |
| ・ |
Camille and Henry Dreyfus Award, 1981 |
| ・ |
Searle Scholar Award, 1983-1986 |
| ・ |
American Society of Biochemistry and Molecular Biology Young Investigator Award, 1991 |
| ・ |
George Ledlie Prize, 1991 |
| ・ |
Richard Lounsbery Award, National Academy of Science, 1995 |
| ・ |
Member, American Academy of Arts and Sciences, 1995 |
| ・ |
Member, National Academy of Arts and Sciences, 1995 |
| ・ |
Honorary Member, Japanese Biochemical Society, 1996 |
|
| Scientific Journals |
|
| ・ |
USA Editor of Development |
| ・ |
Editor of the journal Neurobiology |
| ・ |
Editor of Cytokine & Growth Factor Reviews |
| ・ |
Editor of journal Science |
| ・ |
Editor of Publications of the National Academy of Science |
| ・ |
Editor of electronic journal Regenerative Medicine |
| ・ |
Advisory Board, Genome Biology |
|
| Research field |
|
Research in our laboratory is focused on the developmental biology of the pancreas. We wish to understand how the pancreas normally develops and use that information to grow and develop pancreatic cells (Islets of Langerhans) in culture. These goals challenge us to understand the precursors or stem cells that give rise to the pancreas and to characterize the key gene products that specify cell fates and functions during organogenesis. To this end, we use several vertebrate organisms, including frogs, chickens, and zebrafish, but the majority of our studies are done with mice. We use a wide variety of techniques including functional genomics and gene arrays for gene discovery, tissue explants and grafting for analyzing inductive signals, and developmental genetics for direct assays of gene function. The aim of all our experiments is to understand the genes and cells that direct pancreatic organogenesis. |
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