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JST Press Release

July 21, 2015
Japan Science and Technology Agency (JST)
5-3, Yonbancho, Chiyoda-ku, Tokyo 102-8666

Identification of a macrophage subset that promotes intestinal inflammation
- A novel therapeutic target for the suppression of mucosal injury -

Researcher Information

Research Area “ Elucidation and control of the mechanisms underlying chronic inflammation”
Research Theme “ Development of Sentinel Cell-targeted Therapy for Inflammatory Bowel Diseases”

Journal Information

Authors: Kenichi Asano, Naomichi Takahashi, Mikiko Ushiki, Misa Monya, Fumiaki Aihara, Erika Kuboki, Shigetaka Moriyama, Mayumi Iida, Hiroshi Kitamura, Chun-Hong Qiu, Takashi Watanabe, and Masato Tanaka. “Intestinal CD169+ macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes”. Nature Communications, Published online 21 July 2015, doi: 10.1038/ncomms8802.


[About Research]
Kenichi Asano, M.D., Ph.D.
Associate Professor, Laboratory of Immune Regulation, School of Life Science, Tokyo University of Pharmacy and Life Sciences
URL: http://toyaku-ls-immune.com/en/index.html

[About Program]
Koji Matsuo, Tetsu Kawaguchi, and Shinichi Kato
Life Innovation Group, Department of Innovation Research, JST


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