Taishin Akiyama　　Result

(17)Mouri Y., Yano M., Shinzawa M., Shimo Y., Hirota F., Nishikawa Y, Nii T., Kiyonari H., Abe T., Uehara H., Izumi K., Tamada K., Chen L., Penninger JM., Inoue J., Akiyama T, and Matsumoto M. "Lymphotoxin Signal Promotes Thymic Organogenesis by Eliciting RANK Expression in the Embryonic Thymic Stroma " J. Immunol.,2011 May1;186(9)5047-57

(16)Shimo Y., Yanai H., Ohshima D., Qin J., Motegi H., Maruyama Y., Hori S., Inoue J., and Akiyama T . "TRAF6 directs commitment to regulatory T cells in thymocytes" Gene Cells,2011 Apr. 16(4) 43-47

(15) Oral presentation" Immune recognition" Awaji International Forum on Infection and Immunity on Sep.7.2010

(14) Oral presentation" TRAF6 controls commitment to regulatory T-cell lineage and T-cell receptor signals in thymocytes" 14th International Congress of Immunology on Aug.24.2010

(13) Poster presentation :"A negative feedback regulation of medullary thymic epithelial cell development by RANK signal-dependent expression of osteoprotegerin" at the 14th International Congress of Immunology on Aug. 23.2010.

(12) Oral presentation" RANKL-RANK-OPG system in establishment of immunological tolerance" 3rd International Conference on Osteoimmunology at the Greece on Jun.24.2010

(11) Oral presentation" Development of thymic niches essential for preventing autoimmunity" 1st Internationa Conferece on Frontiers of Regenerative Medicine and Biomedical Science at the China on May.15.2010

(10) Oral presentation "The TNF-family receptors RANK and CD40 cooperatively establish central tolerance in thymus " 12th International TNF conference

(9)Oral presentation:"Roles of RANKL-RANK-OPG system on developments of mTECs and Tregs" at the ThymOZ IV; an internatinal workshop on T lymphocytes on Mar.22.2010.

(8) Oral presentation:"Molecular mechanisms essenital for establishing immunological tolerance in thymus" at the first CSI/JSI/KAI Joint Symposium on Immunology,Shanghai, China on Nov.7.2009

(7) Invitation Lecture:"Signals dicatate central tolerance in thymus" at the 16th Eas Asia Joint Conference on Biomedical Research on Jul.1.2009

(6) Oral presentation:"A CELL AUTONOMOUS REQUIREMENT FOR TRAF6 IN THE DEVELOPMENT OF NATURALLY OCCURRING REGULATORY T CELLS " at the KTCC International Workshop on T Lymphocytes on Jun.4.2009

(5) Oral presentation:"The TNF-family receptors RANK and CD40 cooperatively establish central tolerance in thymus " at the 12th International TNF conference on Apl.28.2009

(4) Oral presentation: "RANK and CD40 cooperatively control central tolerance in thymus" at the ThymUS2008 International (San Juan,Puerto Rico) on Nov.12.2008.

(3) Hikosaka Y, Nitta T, Ohigashi I, Yano K, Ishimaru N, Hayashi Y, Matsumoto M, Matsuo K, Penninger JM, Takayanagi H, Yokota Y, Yamada H, Yosikai Y, Inoue J, Akiyama T, & Takahama Y. "The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator" Immunity, 29, 438-450 (2008).

(2) Press release on Sep.18,2008.:Akiyama T, Shimo Y, Yanai H, Qin J, Ohsima, D, Maruyama Y, Asaumi Y, Kitazawa J, Takayanagi H, Penninger JM, Matsumoto M, Nitta T, Takahama Y, & Inoue J. "The Tumor necrosis family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance" Immunity, 29, 423-437 (2008).

(1) Oral presentation: The 37th annual meeting of Japanese Society for Immunology at Shinagawa on Nov. 20, 2007.