Molecular mechanisms underlying the structural changes of mRNPs
Research Site : Senior Research Scientist, ASI, RIKEN
Abstract
mRNAs in eukaryotic cells are always associated with a specific set of proteins to form messenger ribonucleoproteins (mRNPs). It is presumed that the structural organization of mRNPs is changed (remodeled) during each step of gene regulation. In this project, I try to understand how translation and mRNA stability are regulated by the structural changes of mRNPs.
