Synthesis and stabilization of functional non-coding RNAs in chloroplasts
Research Site : Assistant Professor, Laboratory of Plant Molecular Genetics, Department of Botany, Graduate School of Science , Kyoto University
Abstract
Chloroplasts maintain their own genomes and gene expression machineries. Recently, chloroplast biotechnology is being developed to synthesize biopharmaceutical proteins such as vaccines. In this research, we focus on the stability of RNA in chloroplasts and try to understand protein factors and RNA structures that modulate RNA stability in chloroplasts. Further understandings of chloroplastic RNA stability control may lead to development of techniques to mass produce functional non-coding RNAs with complex secondary- or tertiary structures by chloroplast biotechnology.
