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HOME > Researchers & Research Theme | 2nd term | Shuji Ishihara |
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Shuji Ishihara |
Assistant professor, Department of Basic Science, Graduate School of Arts and Sciences,
University of Tokyo |
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Mechanical processes in morphogenesis : from molecules, cells, to tissues |
In the developmental process of multi-cellular organism, the morphological deformation of tissues occur in a dynamic manner. Forces inducing these changes are derived from cooperative behaviors of cells, such as stiffening and adhesions, which are further controlled by the activities of molecules in the cells. Adopting fruit fly epithelial tissues as model systems, this study aims to reveal how molecule- and cell-level dynamics bring the mechanical properties of the tissue that is responsible for the morphogenesis. |
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