 |
| Authors |
Kanako Tatsumi, Harumi Yamamoto-Mukai, Ritsuko Shimizu, Satoshi Waguri, Yu-Shin Sou, Ayako Sakamoto, Choji Taya, Hiroshi Shitara, Takahiko Hara, Chin Ha Chung, Keiji Tanaka, Masayuki Yamamoto, Masaaki Komatsu |
| Title |
The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice |
| Publication |
Nat. Commun. 2 : 181 doi:10.1038/ncomms1182 (2011) |
| Authors |
Masaaki Komatsu, Hirofumi Kurokawa, Satoshi Waguri, Keiko Taguchi, Akira Kobayashi, Yoshinobu Ichimura, Yu-Shin Sou, Izumi Ueno, Ayako Sakamoto, Kit I. Tong, Mihee Kim, Yasumasa Nishito, Shun-ichiro Iemura, Tohru Natsume, Takashi Ueno, Eiki Kominami, Hozumi Motohashi, Keiji Tanaka, Masayuki Yamamoto |
| Title |
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 |
| Publication |
Nature Cell Biology, vol. 23, 2496-2506 (2009) |
| Authors |
Yong Zhang, Scott Goldman, Rebecca Baerga, Yun Zhao, Masaaki Komatsu, Shengkan Jin |
| Title |
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis |
| Publication |
Proc. Natl. Acad. Sci. USA, vol. 106, 19860-19865 (2009) |
| Authors |
Masaaki Komatsu |
| Title |
Important roles of autophagy-specific substrate p62 in environmental stress response |
| Publication |
EMBO Conference AUTOPHAGY Cell biology, Physiology & Pathology, Monte Verita, Ascona, Switzerland (2009/10/18-21) |
| Authors |
Masaaki Komatsu |
| Title |
Important roles of autophagy-specific substrate p62 in environmental stress response |
| Publication |
5th International Symposium on Autophagy, Otsu, Shiga, Japan (2009/9/24-28) |
| Authors |
Nishida, Y., Arakawa, S., Fujitani, K., Yamaguchi, H., Mizuta, T., Kanaseki, T., Komatsu, M., Otsu, K., Tsujimoto, Y., Shimizu, S. |
| Title |
Discovery of Atg5/Atg7-independent alternative macroautophagy |
| Publication |
Nature, vol. 458, 1131-1135 (2009) |
| Authors |
Shibata, M., Yoshimura, K., Furuya, N., Koike, M., Ueno, T., Komatsu, M., Arai, H., Tanaka, K., Kominami, E., Uchiyama, Y. |
| Title |
The MAP1-LC3 conjugation system is involved in lipid droplet formation |
| Publication |
Biochem. Biophys. Res. Commun., vol. 382, 419-423 (2009) |
| Authors |
Huett, A., Ng, A., Cao, Z., Kuballa, P., Komatsu, M., Daly, MJ., Podolsky, DK., Xavier RJ. |
| Title |
A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy |
| Publication |
J. Immunol., vol. 182, 4917-44930 (2009) |
| Authors |
Pua, HH., Guo, J., Komatsu, M., He, YW. |
| Title |
Autophagy is essential for mitochondrial clearance in mature T lymphocytes |
| Publication |
J. Immunol., vol. 182, 4045-4055 (2009) |
| Authors |
Rajat Singh, Susmita Kaushik, Yongjun Wang, Youqing Xiang, Inna Novak, Masaaki Komatsu, Keiji Tanaka, Ana Maria Cuervo, Mark J. Czaja |
| Title |
Autophagy regulates lipid metabolism |
| Publication |
Nature, vol. 458, 1131-1135 (2009) |
| Authors |
Yue, Z., Friedman, L., Komatsu, M., Tanaka, K. |
| Title |
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases |
| Publication |
Biochem. Biophys. Acta Mol. Cell Res., vol. 1793, 1496-1507 (2009) |
| Authors |
Kirkin, V., Lamark, T., Sou, YS., Bjørkøy, G., Nunn, JL., Bruun, JA., Shvets, E., McEwan, DG., Clausen, TH., Wild, P., Bilusic, I., Theurillat, JP., øvervatn, A., Ishii, T., Elazar, Z., Komatsu M., Dikic, I., Johansen, T. |
| Title |
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates |
| Publication |
Mol. Cell, vol. 33, 505-516 (2009) |
| Authors |
Masaaki Komatsu |
| Title |
Inclusion Body Precipitated by Autophagy-Deficiency |
| Publication |
Keystone Symposia Neurodegenerative Diseases: New Molecular Mechanisms, Colorado, USA (2009/2/18) |
| Authors |
Masaaki Komatsu |
| Title |
Important roles of autopahgy-specific substrate p62 in environmental stress response |
| Publication |
Molecular Mechanism of Environmental Response to Food and Oxygen III, Sendai, Japan (2009/2/10) |
| Authors |
Masaaki Komatsu |
| Title |
Inclusion body in autophagy-deficient mice |
| Publication |
The 15th Takeda Science Foundation Symposium on Bioscience "Cell Death: what have we learned and what will we learn?, Tokyo, Japan (2008/12/1) |
| Authors |
Masaaki Komatsu |
| Title |
Overview of Autophagy -The Physiological roles and Remaining Issues- |
| Publication |
Surugadai School, Advanced Course of Biomedical Science, Tokyo, Japan (2008/11/6) |
| Authors |
Ueno T., Sato W., Horie Y., Komatsu M., Tanida I., Yoshida M., Ohshima S., Mak TW., Watanabe S., Kominami E. |
| Title |
Loss of PTEN, a tumor suppressor, caused the strong inhibition of autophagy without affecting LC3 lipidation |
| Publication |
Autophagy, vol. 5, 692-700 (2008) |
| Authors |
Saitoh T., Fujita N., Jang MH., Uematsu S., Yang BG., Satoh T., Omori H., Noda T., Yamamoto N., Komatsu M., Tanaka K., Kawai T., Tsujimura T., Takeuchi O, Yoshimori T., Akira S. |
| Title |
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production |
| Publication |
Nature, vol. 456, 264-268 (2008) |
| Authors |
Chie Ebato, Toyoyoshi Uchida, Masayuki Arakawa, Masaaki Komatsu, Takashi Ueno, Koji Komiya, Kosuke Azuma, Takahisa Hirose, Keiji Tanaka, Eiki Kominami, Ryuzo Kawamori, Yoshio Fujitani, Hirotaka Watada |
| Title |
Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet |
| Publication |
Cell Metabolism, vol. 8, 325-332 (2008) |
| Authors |
Hye Seung Jung, Kun Wook Chung, Jeong Won Kim, Jin Kim, Masaaki Komatsu, Keiji Tanaka, Yen Hoang Nguyen, Tong Mook Kang, Kun-Ho Yoon, Ji-Won Kim, Yeon Taek Jeong, Myoung Sook Han, Moon-Kyu Lee, Kwang-Won Kim, Jaekyoon Shin, Myung-Shik Lee |
| Title |
Loss of Autophagy Diminishes Pancreatic Cell Mass and Function with Resultant Hyperglycemia |
| Publication |
Cell Metabolism, vol. 8, 318-324 (2008) |
| Authors |
Sou YS, Waguri S, Iwata JI, Ueno T, Fujimura T, Hara T, Sawada N, Yamada A, Mizushima N, Uchiyama Y, Kominami E, Tanakak K, Komatsu M |
| Title |
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice |
| Publication |
Molecular Biology of the Cell, vol. 19, 4762-4775 (2008) |
| Authors |
Ichimura Y, Kominami E, Tanaka K, Komatsu M |
| Title |
Selective turnover of p62/A170/Sqstm1 by autophagy |
| Publication |
Autophagy, vol. 4, 1063-1066 (2008) |
| Authors |
Waguri S, Komatsu M |
| Title |
Biochemical and Morphological Detection of Inclusion Bodies in Autophagy-deficient Mice |
| Publication |
Method in Enzymology, vol. 453, 181-196 (2009) |
| Authors |
Ichimura Y, Kumanomidou T, Sou YS, Mizushima T, Ezaki J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M |
| Title |
Structural Basis for Sorting Mechanism of p62 in Selective Autophagy |
| Publication |
J. Biol. Chem., vol. 283, 22847-22857 (2008) |
| Authors |
Oppenheim RW, Blomgren K, Ethell DW, Koike M, Komatsu M, Prevette D, Roth KA, Uchiyama Y, Vinsant S, Zhu C |
| Title |
Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy |
| Publication |
J Neurosci., vol. 28, 1490-1497 (2008) |
| Authors |
Matsumoto N, Ezaki J, Komatsu M, Takahashi K, Mineki R, Taka H, Kikkawa M, Fujimura T, Takeda-Ezaki M, Ueno T, Tanaka K, Kominami E |
| Title |
Comprehensive proteomics analysis of autophagy-deficient mouse liver |
| Publication |
Biochem. Biophys. Res. Commun., vol. 368, 643-649 (2008) |
| Authors |
Klionsky D.J., Komatsu M., et al. |
| Title |
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes |
| Publication |
Autophagy, vol. 4, 151-175 (2008) |
| Authors |
Yue Z, Wang QJ, Komatsu M |
| Title |
Neuronal autophagy: going the distance to the axon |
| Publication |
Autophagy, vol. 4, 94-96 (2008) |
| Authors |
Masaaki Komatsu |
| Title |
Role of p62/SQSTM1 degradation by autophagy in cytoplasmic inclusion formation |
| Publication |
GRC Autophagy in Stress, Development and Disease, Ventura, CA, USA (2008/1/10) |
| Authors |
Koike, M., Shibata, M., Tadakoshi, M., Gotoh, K., Komatsu, M., Waguri, S., Kawahara, N., Kuida, K., Nagata, S., Kominami, E., Tanaka, K., Uchiyama, Y. |
| Title |
Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury |
| Publication |
Am. J. Pathol., vol. 172, 454-469 (2008) |
| Authors |
Miguel A. Sanjuan, Christopher P. Dillon, Stephen W. G. Tait, Simon Moshiach, Frank Dorsey, Samuel Connell, Masaaki Komatsu, Keiji Tanaka, John L. Cleveland, Sebo Withoff, Douglas R. Green |
| Title |
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis |
| Publication |
Nature, vol. 450, 1253-1257 (2007) |
| Authors |
Masaaki Komatsu, Satoshi Waguri, Masato Koike, Yu-shin Sou, Takashi Ueno, Taichi Hara, Noboru Mizushima, Jun-ichi Iwata, Junji Ezaki, Shigeo Murata, Jun Hamazaki, Yasumasa Nishito, Shun-ichiro Iemura, Tohru Natsume, Toru Yanagawa, Junya Uwayama, Eiji Warabi, Hiroshi Yoshida, Tetsuro Ishii, Akira Kobayashi, Masayuki Yamamoto, Zhenyu Yue, Yasuo Uchiyama, Eiki Kominami, Keiji Tanaka |
| Title |
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice |
| Publication |
Cell, vol. 131, 1149-1163 (2007) |
| Authors |
Komatsu M, Ueno T, Mizushima T, Tatsumi K, Ozaki Y, Kawakami T, Suzuki A, Ogasahara K, Komatsu M, Kominami E, Tanaka K, Yamane T. |
| Title |
Crystal structure of Ufc1, the Ufm1-conjugating enzyme |
| Publication |
Biochem. Biophys. Res. Commun., vol. 362, 1079-1084 (2007) |
| Authors |
Masaaki Komatsu, Qing Jun Wang, Gay R. Holstein, Victor L. Friedrich Jr, Jun-ichi Iwata, Eiki Kominami, Brian T. Chait, Keiji Tanaka, Zhenyu Yue |
| Title |
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration |
| Publication |
Proceedings of the National Academy of Sciences, vol. 104, 14489-94 (2007) |
| Authors |
Masaaki Komatsu |
| Title |
Selective Autophagy Regulates Formation of Intracytoplamic Inclusions |
| Publication |
Keystone Symposium on Autophagy in Health and Disease, Monterey, USA (2007/4/19) |
| Authors |
Komatsu M, Ueno T, Waguri S, Uchiyama Y, Kominami E, Tanaka K |
| Title |
Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons |
| Publication |
Cell Death and Differentiation, vol. 14, 887-894 (2007) |
| Authors |
Kang SH, Kim GR, Seong M, Baek SH, Seol JH, Bang OS, Ovaa H, Tatsumi K, Komatsu M, Tanaka K, Chung CH |
| Title |
Two novel ubiquitin-fold modifier 1 (Ufm1)-specific Proteases, UfSP1 and UfSP2 |
| Publication |
J. Biol. Chem., vol. 282, 5256-5262 (2007) |
| Authors |
Masaaki Komatsu, Keiji Tanaka |
| Title |
Ablation of constitutive autophagy in neural cells causes neurodegeneration in mice |
| Publication |
The 4th Congress of Federation of Asian-Oceanian Neuroscience Societies, Hong Kong, China (2006/12/1) |
| Authors |
Masaaki Komatsu, Keiji Tanaka, Eiki Kominami |
| Title |
Selective autophagy suppresses the formation of ubiquitin-positive aggregates |
| Publication |
4th International Symposium of Autophagy, Mishima, Japan (2006/10/2) |
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