Japan Science and Technology Agency. Metabolism and cellular Function PRESTO
Japanese English Japan Science and Technology Agency. PRESTO
Resercher, Research Theme
Takayuki Shindo
Phase II (2006-2009)
Photo
Research Site
Professor, Department of Organ Regeneration, Graduate School of Medicine, Shinshu University
Research Reports
http://www.metabolism.jst.go.jp/en/ronbun/shindo.html
Theme
Pathophysiological analysis of receptor-activity-modifying protein and development of a new therapy for vascular diseases
Abstract
Adrenomedullin (AM) is a peptide, which possess various biological activities, including organ-protective effects, and anti-atherosclerotic effects. These biological activities of AM are controlled by receptor-activity-modifying proteins (RAMPs). In this study, I will clarify the pathophysiological roles of AM-RAMP system by using a series of genetically-engineered mice and aim at development of a new therapy for metabolic syndrome and vascular diseases.


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