Osamu Matoba
Brain-Optical Computing through Holographic Measurement and Manipulation of Brain Activity
Grant No.：JPMJCR25R1
Research Director
Osamu Matoba
Professor
Center of Optical Scattering Image Science
Kobe University
Collaborator
| Hiroko Shimada | Project Lecturer Frontier Research & Education Collaborative Square Keio University |
| Hideyuki Suzuki | Professor Graduate School of Information Science and Technology The University of Osaka |
| Hiroaki Wake | Professor National Institute for Physiological Sciences National Institute of Natural Sciences |
Outline
This project aims to achieve “brain-optical computing” by developing a “Holographic Light Interface (HLI)” for measuring and manipulating brain activity. We will experimentally and theoretically demonstrate the first application of information processing in the mouse brain or brain organoids for computation. We believe that this technology will bring revolutionary advances to diverse fields in both engineering and culture, including automatic control, decision-making, language processing, advanced computing, and artistic creation, by enabling efficient information processing of living organisms.
Takeo Minamikawa
Innovative biomedical sensing driven by quasiparticle interactions
Grant No.：JPMJCR25R2
Research Director
Takeo Minamikawa
Professor
Graduate School of Engineering Science
The University of Osaka
Collaborator
| Koichi Tsuneyama | Professor Graduate School of Biomedical Sciences Tokushima University |
| Eiji Hase | Associate Professor Institute of Post-LED Photonics Tokushima University |
Outline
In this study, we explore a novel concept of remote plasmonic molecular spectroscopy. This approach is based on complex interactions among multiple quasiparticles such as photons, phonons, and plasmons, as well as their coupling with molecular dipoles. This emerging spectroscopic framework enables high-sensitivity, quantitative, and comprehensive analysis of biomolecular information. Through applications to pathological diagnostics, we seek to advance our understanding of disease pathology, improve diagnostic accuracy, and support the development of sustainable infrastructures for next-generation medicine.
Yasuyuki Yokota
Development of Innovative Diagnostic and Repair Systems for Electrochemical Interfaces Based on Optical Sensing
Grant No.：JPMJCR25R3
Research Director
Yasuyuki Yokota
Senior Research Scientist
Pioneering Research Institute
RIKEN
Collaborator
| Yasunobu Ando | Associate Professor Institute of Integrated Research Institute of Science Tokyo |
| Takashi Yamamoto | Associate Professor Faculty of Science and Technology Keio University |
Outline
The solid-liquid interface that governs the performance of electrochemical devices is extremely complex, making it difficult to rapidly obtain crucial information such as functional responses and degradation status. In this study, we will develop optical sensing method for electrochemical interfaces that can be integrated with information science, enabling innovative diagnostic and repair technologies that were difficult to achieve with conventional current-voltage measurements. By bringing together researchers in multiscale spectroscopy, materials and devices, and information and computational science, we aim to construct green information systems that contribute to the realization of a sustainable society.
