[Biological Functions] Understanding and Designing Biological Functions

Strategic Objective

Challenging to create suprabiological tissue

Measuring “resilience of life” - Discovery and exploration of unknown biological response mechanisms

Development of innovative cell manipulation technologies and elucidation of cellular regulatory mechanisms

Elucidation of the mechanisms relating to changes in biological robustness associated with aging and control of age-related diseases

Toward scientific discoveries through DX in life science research

Integrated understanding of human multi-sensing networks and elucidation of their control mechanisms

Design of plant-derived molecules building up the foundation for plant synthetic biology

Functional dynamics in the cell

Research Supervisor

pic

Masahito Ikawa(Professor, Research Institute for Microbial Diseases, The University of Osaka)

Overview

 This Research Area aims to “deepen understanding of biological functions through innovative ideas and technologies” and “evolution of ingenious design of biological functions based on understandings”, bring virtuous cycles through the synergistic effects of both, and create results that lead to innovation and revolution in life science research fields.
 Specifically, research on “understanding biological functions” includes the discovery and elucidation of functions through unprecedented high-resolution or high-sensitivity observation, measurement, profiling, etc. Additionally, research on “designing biological functions” includes genome editing technology and its advanced developments, or modification of biological functions by functional molecules, or the creating new biological functions.
 The target biological functions are gene expression, protein synthesis, modification, metabolism, degradation, information transmission within and between cells and tissues, reproduction, development, differentiation, regeneration, aging, immunity, biological defense, symbiosis, memory, learning, and biological rhythms. The target organisms are not restricted to animals, but also include plants, microorganisms and others. In other words, there are no restrictions on the research targets, but research must be challenging and based on unprecedented, innovative ideas and technologies.
 In implementing research, we prioritize the development of researchers and emphasize the establishment of platforms for interaction and mutual inspiration among young researchers from different research areas. Furthermore, active efforts are made to build a broad human network that will facilitate future collaborations among researchers.

Research Area Advisors

Hiroshi Asahara Professor, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo
Tohru Ishitani Professor, Research Institute for Microbial Diseases, The University of Osaka
Noriko Osumi Professor, Graduate School of Medicine, Tohoku University
Sadao Ota Professor, Research Center for Advanced Science and Technology, The University of Tokyo
Yuki Okada Professor, Institute for Quantitative Biosciences, The University of Tokyo
Shinsuke Sando Professor, Graduate School of Engineering, The University of Tokyo
Akiko Takahashi Chief, Division of Cellular Senescence, Cancer Institute, Japanese Foundation for Cancer Research/Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo
Osamu Takeuchi Professor, Graduate School of Medicine, Kyoto University
Masao Doi Professor, Graduate School of Pharmaceutical Sciences, Kyoto University
Takeharu Nagai Vice Director, Proffser, SANKEN, The University of Osaka
Michitaka Notaguchi Professor, Department of Botany, Graduate School of Science, Kyoto University
Takeshi Bamba Professor, Medical Institute of Bioregulation, Kyushu University
Takema Fukatsu Prime Senior Researcher, National Institute of Advanced Industrial Science and Technology (AIST)/Professor, The University of Tokyo/Professor, University of Tsukuba
Akira Funahashi Professor, Faculty of Science and Technology, Keio University
Tomoji Mashimo Professor, The Institute of Medical Science, The University of Tokyo

Quick Access

Program

  • CREST
  • PRESTO
  • ERATO
  • ACT-X
  • ALCA
  • CRONOS
  • AIP Network Lab
  • Global Activities
  • Diversity
  • SDGs
  • OSpolicy
  • Yuugu
  • Questions