Topics

Team Leader

Group Leader

AIZAWA Yasunori
SHIMAKAWA Ginga
SHIRASU Ken
SUGIYAMA Akifumi
SEKI Motoaki
TAMAKI Hideyuki
NISHIMURA Yuki
NOMURA Nobuhiko
MIZUTANI Masaharu

Co-Principal Investigator

ARITA Masanori
ISHIZAKI Kimitsune
ISHIBASHI Yushi
ISOGAI Shota
IWASAKI Takashi
OHKUMA Moriya
OSAKABE Yuriko
KAJIKAWA Masataka
KURASAWA Hikaru
SAZUKA Takashi
SHIMIZU Takayuki
SHIRAI Tomokazu
SHIRAISHI Kosuke
SUGIMOTO Keiko
SEKI Hikaru
TAKAGI Hiroshi
TAKEMURA Miho
TANAKA Kan
TOYOTA Tomoyo
NAKAMURA Yuki
NIKAIDO Masato
MATSUI Motomu
MIURA Kenji
MINE Akira

Summary

Conventional biomanufacturing today utilize biomass such as sugar produced in agriculture, which does not directly contribute to reducing CO₂ emissions and has problems such as competition with food. Also, the types of compounds produced by microorganisms such as E. coli and yeast are limited due to their metabolic constraints. Therefore, by utilizing the diverse metabolic abilities of plants or others, we will create an innovative manufacturing platform with still under developing plants, microalgae, and new CO₂ -fixing microorganisms as hosts using CO₂ as a direct raw material for manufacturing. We will collect their biological information, and develop cutting-edge technologies of metabolic design, artificial genome construction, large-scale genome modification, gene introduction, and differentiation control for them. While applying these technologies, we will expand production and improve productivity of useful compounds that have been difficult to produce so far.

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Summary (670KB)

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