所属学会

日本分析化学会、日本農芸化学会

研　究

分析化学手法(MSn、nanoLC-MSn、等)を用いた複合糖質の解析

研究業績

〔論文〕 Suzuki, K. Daikoku, S. Son, S-H. Ito Y. Kanie, O. “Synthetic study of 3-fluorinated sialic acid derivatives”, Carbohydrate Research 2015, 406, 1-9. Daikoku, S. Seko, A. Ito, Y. Kanie, O. “Glycan structure and site of glycosylation in the ER-resident glycoprotein, uridine 5'-diphosphate-glucose: glycoprotein glucosyltransferases 1 from rat, porcine, bovine, and human”, Biochem. Biophys. Res. Commun. 2014, 451, 356-360. Son, S-H. Daikoku, S. Ohtake, A. Suzuki, K. Kabayama, K. Ito Y. Kanie, O. “Syntheses of lactosyl ceramide analogues carrying novel bifunctional BODIPY dyes directed towards the differential analysis of multiplexed glycosphingolipids by MS/MS using iTRAQ”, Chem. Commun. 2014, 50, 3010–3013. Takeda, Y. Seko, A. Hachisu, M. Daikoku, S. Izumi, M. Koizumi, A. Fujikawa, K. Kajihara, Y. Ito, Y. “Both Isoforms of Human UDP-glucose:glycoprotein Glucosyltransferase are Enzymatically Active”, Glycobiology 2014, 24, 344–350. Shioiri, Y. Suzuki, K. Daikoku, S. Kurimoto, A. Ito, Y. Kanie, O. “Stereospecific generation and analysis of α- and β-hemiacetals of monosaccharides in gas phase”, Carbohydrate Res. 2013, 382, 43–51. Ohtake, A. Daikoku, S. Suzuki, K. Ito, Y. Kanie, O. “Analysis of the cellular dynamics of fluorescently tagged glycosphingolipids by using a nanoLC-MS/MS platform”, Anal. Chem., 2013, 85, 8475-8482. Kanie, O. Kanie, Y. Daikoku, S. Shioiri, Y. Kurimoto, A. Mutsuga, S. Goto, S. Ito, Y. Suzuki, K. “Multi‐stage mass spectrometric information obtained by deconvolution of energy‐resolved spectra acquired by triplequadrupole mass spectrometry”, Rapid Commun. Mass Spectrom., 2011, 25, 1617-1624. Daikoku, S. Ono, Y. Ohtake, A. Hasegawa, Y. Fukusaki, E. Suzuki, K. Ito, Y. Goto S. Kanie O. “Fluorescence-monitored zero dead-volume nanoLC-microESI-QIT-TOF MS for analysis of fluorescently tagged glycosphingolipids”, Analyst, 2011, 136, 1046-1050. Daikoku, S. Widmalm G. Kanie, O. ”Analysis of a series of isomeric oligosaccharides based on energy-resolved mass spectrometry: A challenge on homobranched trisaccharides”, Rapid Commun. Mass Spectrom, 2009, Nov 9, 23(23), 3713-3719. Suzuki, K. Tobe, A. Adachi, S. Daikoku, S. Hasegawa, Y. Shioiri, Y. Kobayashi, M. Kanie, O. “N-n-Hexyl-4-aminobutyl glycosides in the structural and biological investigations of oligosaccharide”, Org. Biomol. Chem., 2009, 7, 4726-4733. Kanie, O. Kurimoto, A. Daikoku, S. Mutsuga, S. Kanie, Y. Suzuki, K. ”Analysis of behavior of sodiated sugar hemiacetales under low-energy collision-induced dissociation condition and application to investigating mutarortation and mechanism of a glycosidase” Proc. Jpn Acad. Ser. B, 2009, 85, 204-215. Daikoku, S. Kurimoto, A. Mutsuga, S, Ako, T. Kanemitsu, T. Shioiri, Y. Ohtake, A. Kato, R. Saotome, C. Ohtsuka, I. Koroghi, S. Sarker, S. K. Tobe, A. Adachi, S. Suzuki, K. Kanie, O. “Ion-trap mass spectrometry unveils the presence of isomeric oligosaccharides in an analyte: Stage-discriminated correlation of energy-resolved mass spectrometry” Carbohydr. Res., 2009, 344-394. Shioiri, Y. Kurimoto, A. Ako, T. Daikoku, S. Ohtake, A. Ishida, H. Kiso, M. Suziki, K. Kanie, O. “Energy-resolved structural details obtained from gangliosides”, Anal. Chem., 2009, 81, 139-145. Ono, Y. Kitajima, M. Daikoku, S. Shiroya, T. Nishihara, S. Kanie, Y. Suzuki, K. Goto, S. Kanie, O. ”Sequential enzymatic glycosyltransfer reactions on a microfluidic device: Synthesis of a glycosaminoglycan linkage region tetrasaccharide” Lab. Chip., 2008, 8, 2168-2173. Suzuki, K. Daikoku, S. Ako, T. Shioiri, Y. Kurimoto, A. Ohtake, A. Sarkar, S. K. Kanie, O. “High yielding and controlled dissociation of glycosides producing B- and C-ion species under CID MS/MS conditions and use in structure determination”, Anal Chem., 2007, 79, 9022-9029. Daikoku, S. Ako, T. Kato, R. Ohtsuka, I. Kanie, O. ”Discrimination of 16 structural isomers of fucosyl galactose based on energy-resolved mass spectrometry (ERMS)”, J. Am. Soc. Mass Spectrom., 2007, 18, 1873-1879. Daikoku, S. Ako, T. Kurimoto, A. Kanie, O. ”Anomeric information obtained from a series of synthetic trisaccharides using energy-resolved mass spectra”, J. Mass Spectrom., 2007, 42, 714-723. Ako, T. Daikoku, S. Ohtsuka, I. Kato, R. Kanie, O. ”A method of orthogonal oligosaccharide synthesis leading to combinatorial library based on stationary solid-phase reaction”, Chem. Asian J., 2006, 1, 798-813. Ohtsuka, I. Ako, T. Kato, R. Daikoku, S. Koroghi, S. Kanemitsu, T. Kanie, O. ”Synthesis of a fucosyl galactose library consisting of a complete set of anomeric configurations and linkage positions”, Carbohydr. Res., 2006, 341, 1476-1487. Kanie, O. Ohtsuka, I. Ako, T. Daikoku, S. Kanie, Y. Kato, R. ”Orthogonal glycosylation reactions on solid-phase and the synthesis of a library consisting of complete set of fucosyl galactose isomers”, Angew. Chem. Int. Ed., 2006, 45, 3851-3854. Jin, Y. Hada, N, Oka, J. Kanie, O. Daikoku, S. Kanie, Y. Yamada, H. Takeda, T. ”Syntheses of model compounds related to an antigenic epitope in pectic polysaccharides from Bupleurum falcatum L. (Ⅱ)”, Chem. Pharm. Bull., 2006, 54, 485-492. Kanemitsu, T. Daikoku, S. Kanie, O. “Solid-phase synthesis of sialyl Tn antigen”, J. Carbohydr. Chem., 2006, 25, 361-376. Kurimoto, A. Daikoku, S. Mutsuga, S. Kanie, O. ”Analysis of energy-resolved mass spectra at MSn in a pursuit to characterized isomers of oligosaccharides”, Anal. Chem., 2006, 78, 3461-3466. 〔Book Chapter〕 Kurimoto, A. Daikoku, S. Kanie, O. ”Energy-resolved mass spectrometry (ERMS) of oligosaccharide in Experimental Glycoscience, Glycobiology”, Springer, Ed. Taniguchi, N., 2008, 37-38 〔特許〕 Method of Analyzing Structure of Sugar Chain Publication data : 2007-07-25 Inventor(s) : Kanie Osamu, Kurimoto Ayako, Daikoku Shusaku Applicant(S) : Mitsubishi chem. Corp.

メール

daikoku970s[＠]riken.jp