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Japan Science and Technology Agency.

Creation of a novel technology towards diagnosis and treatment based un understanding of molecular pathogenesis of psychiatric and neurological disorders
Research Themes, Principle Investigators

Inokuchi Team

Researcher's name Kaoru Inokuchi
Group Director,
Mitsubishi Kagaku Institute of Life Sciences, MITILS
Research Themes Development of PTSD remedy based on the molecular mechanisms underlying fear memory formation


Post-traumatic stress disorder (PTSD) is triggered by a traumatic experience that is based on strong fear memory. This project aims to understand the molecular mechanisms underlying fear memory formation in animal models. Specifically, we will focus our attention on the molecular and cellular basis of reconsolidation and extinction of fear memory. Based on these results we also attempt to develop a theoretically novel PTSD remedy.