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Team Members

Masaharu NAGAYAMA (Hokkaido University) Team Leader
Mitsuhiro DENDA (Shiseido Company, Limited)

Research Theme

Clarification of dermatological disease mechanisms through collaboration of physiology and mathematical science

Stratum corneum plays an important role as a barrier function, and it is known that its failure relates to various dermatological diseases. We will establish a mathematical model for the dynamics seen in keratinocytes and confirm the validity of the model through physiological experiments. Using the model, we will understand how to realize the barrier function of a skin from the viewpoints of both physiology and mathematical science. Through these approaches, we aim to clarify the cause and treatment of diseases related to the failure of the barrier function.

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