• FY 2010
  • FY 2011
  • FY 2012

  • Koji AOKI
  • Kenichi ASANO
  • Takaharu OKADA
  • Junko SASAKI
  • Katsuaki SATO
  • Takashi SHICHITA
  • Kazuhiro SUZUKI
  • Takashi TANAKA
  • Susumu NAKAE
  • Sachie HIRATSUKA
  • Kumiko MAKIDE
  • Tohru MINAMINO
  • Tadashi YOKOSUKA

Susumu Nakae – Regulation of chronic inflammation by proinflammatory mediators


Susumu Nakae
Associate Professor, Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo
Research Theme
Regulation of chronic inflammation by proinflammatory mediators

Excessive/inappropriate production of proinflammatory mediators by certain immune cells results in the development of chronic inflammatory diseases. On the other hand, the lack of certain proinflammatory mediators/cells also leads to the delayed resolution of inflammation in some cases. Thus, they have a dual role in the setting as proinflammatory and anti-inflammatory mediators/cells. The goals of this study are the clarification of molecular mechanism for the regulation of chronic inflammation by proinflammatory mediators/cells in vivo.

Research Results
The 5 Cardinal Signs of Inflammation