Reserach

Researchers

PRESTOCREST
  • FY 2010
  • FY 2011
  • FY 2012

  • Makoto ARITA
  • Tatsushi IGAKI
  • Naoko OHTANI
  • Masatsugu OH-HORA
  • Shinobu SAIJO
  • Tomohiro SAWA
  • Yuki SUGIURA
  • Kohsuke TAKEDA
  • Norihiko TAKEDA
  • Yasushi HIROTA
  • Kazuyo MORO
  • Masakatsu YAMASHITA
  • Hiroshi WATARAI

Makoto Arita – Establishing the molecular bases of resolution of inflammation as potential therapeutic targets for chronic diseases

Researcher

Makoto Arita
Team Leader, Center for Integrative Medical Sciences, Riken
http://www.riken.jp/en/research/labs/ims/
Research Theme
Establishing the molecular bases of resolution of inflammation as potential therapeutic targets for chronic diseases

In many chronic conditions, sustained inflammation and impaired resolution are suspected as key components of pathogenesis. In this study, we will determine the molecular and cellular events in the resolution phase, and identify immunoregulatory cells and/or mediators involved in the resolution of inflammation. These results will raise the possibility of activating endogenous pro-resolution systems as potential therapeutic targets for human diseases.

Research Results
The 5 Cardinal Signs of Inflammation