Motoyuki Hattori

「Motoyuki Hattori」
Degree
Ph.D.
Position, Research site
Professor, School of Life Sciences, Fudan University
URL
 
Research Field
Structure and Function of Membrane Transporters

Publication

  1. Kasuya G, Fujiwara Y, Takemoto M, Dohmae N, Nakada-Nakura Y, Ishitani R, Hattori M, Nureki O. Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels. Cell Rep. 2016 Feb 2;14(4):932-44. doi: 10.1016/j.celrep.2015.12.087. Epub 2016 Jan 21
  2. Takeda H, Hattori M, Nishizawa T, Yamashita K, Shah ST, Caffrey M, Maturana AD, Ishitani R, Nureki O. Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE. Nat Commun. 2014 Nov 4;5:5374. doi: 10.1038/ncomms6374.
  3. 服部素之「イオンチャネル型細胞外ATP受容体のリガンド認識機構および活性化機構」日本生理学会雑誌　第76巻5号 September 2014 .
  4. Doki S, Kato HE, Solcan N, Iwaki M, Koyama M, Hattori M, Iwase N, Tsukazaki T, Sugita Y, Kandori H, Newstead S, Ishitani R, Nureki O.:Structural basis for dynamic mechanism of proton-coupled symport by the peptide transporter POT. Proc Natl Acad Sci U S A. (2013) 110, 11343-11348.
  5. Baconguis I, Hattori M, Gouaux E.:Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels. Current Opinion in Structural Biology. (2013) 23, 277-284.
  6. Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O.:Structural basis for the drug extrusion mechanism by a MATE multidrug transporter. Nature (2013) 496, 247-251.
  7. Hattori M, Hibbs RE, Gouaux E. (2012) A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening. Structure. 20, 1293-1299.
  8. Imai S, Maruyama T, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I. (2012) Spatial distribution of cytoplasmic domains of the Mg2+-transporter MgtE, in a solution lacking Mg2+, revealed by paramagnetic relaxation enhancement. Biochim Biophys Acta. 1824, 1129-1135.
  9. Hattori M, Gouaux E. (2012) Molecular mechanism of ATP binding and ion channel activation in P2X receptors. Nature. 485, 207-212.
  10. Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I. (2012) Backbone resonance assignments for the cytoplasmic region of the Mg2+ transporter MgtE in the Mg2+-unbound state. Biomol NMR Assign. DOI: 10.1007/s12104-012-9385-y
  11. Hattori M, Iwase N, Furuya N, Tanaka Y, Tsukazaki T, Ishitani R, Maguire ME, Ito K, Maturana A, Nureki O. (2009) Mg2+-dependent gating of bacterial MgtE channel underlies Mg2+ homeostasis. EMBO J. 28, 3602-3612.
  12. Hattori M, Jin Y, Nishimasu H, Tanaka Y, Mochizuki M, Uchiumi T, Ishitani R, Ito K, Nureki O. (2009) Structural basis of novel interactions between the small-GTPase and GDI-like domains in prokaryotic FeoB iron transporter. Structure. 17, 1345-1355.
  13. Jin Y, Hattori M, Nishimasu H, Ishitani R, Nureki O. (2009) Crystallization and preliminary X-ray diffraction analysis of the truncated cytosolic domain of the iron transporter FeoB. Acta Crystallogr Sect F Struct Biol Cryst Commun. 65, 784-787.
  14. Higuchi T, Hattori M, Tanaka Y, Ishitani R, Nureki O. (2009) Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein. Proteins. 76, 768-771.
  15. Nureki O, Hattori M, Ishitani R. (2008) Mechanism of cellular magnesium balance regulation by a magnesium transporter. Seikagaku. 80, 933-939. Review
  16. Ishitani R, Sugita Y, Dohmae N, Furuya N, Hattori M, Nureki O. (2008) Mg2+-sensing mechanism of Mg2+ transporter MgtE probed by molecular dynamics study. Proc Natl Acad Sci U S A. 105, 15393-15398.
  17. Hattori M, Nureki O. (2008) Structural basis for the mechanism of Mg2+ homeostasis by MgtE transporter. Tanpakushitsu Kakusan Koso. 53, 242-248. Review
  18. Hattori M, Tanaka Y, Ishitani R, Nureki O. (2007) Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of a cation diffusion facilitator family protein. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63, 771-773.
  19. Hattori M, Tanaka Y, Fukai S, Ishitani R, Nureki O. (2007) Crystal structure of the MgtE Mg2+ transporter. Nature. 448, 1072-1075.
  20. Hattori M, Tanaka Y, Fukai S, Ishitani R, Nureki O. (2007) Crystallization and preliminary X-ray diffraction analysis of the full-length Mg2+ transporter MgtE. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63, 682-684.
  21. Tanaka Y, Hattori M, Fukai S, Ishitani R, Nureki O. (2007) Crystallization and preliminary X-ray diffraction analysis of the cytosolic domain of the Mg2+ transporter MgtE. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63, 678-681.
  22. Sasaki HM, Sekine S, Sengoku T, Fukunaga R, Hattori M, Utsunomiya Y, Kuroishi C, Kuramitsu S, Shirouzu M, Yokoyama S. (2006) Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase. Proc Natl Acad Sci U S A. 103, 14744-14749.
  23. Hattori M, Mizohata E, Tatsuguchi A, Shibata R, Kishishita S, Murayama K, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S. (2006) Crystal structure of the single-domain rhodanese homologue TTHA0613 from Thermus thermophilus HB8. Proteins. 64, 284-287.
  24. Hattori M, Mizohata E, Manzoku M, Bessho Y, Murayama K, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S. (2005) Crystal structure of the hypothetical protein TTHA1013 from Thermus thermophilus HB8. Proteins. 61, 1117-1120.
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