Shinji Masui Division Chief, Department of Regenerative Medicine, Research Institute, International Medical Center of Japan

Direct reprogramming from patients’ skin, without the step making iPS cells, to a desired cell type for the transplantation should reduce the time for waiting and eliminate troubles of immunological rejection. Trans-differentiation is thought to need activity of multiple genes at the same time, while there is no general method to determine them so far. In this project, I would develop a system to efficiently find a gene set for induction of any cell type.

Homepage URL:http://www.cira.kyoto-u.ac.jp/e/index.html