Establishment of technology to evaluate the all time scales reaction in whole body
Masamichi Yamamoto
Research Site |
Kyoto University |
Graduate School of Medicine |
Specific Lecturer |
Content
Disease is analyzed as an abnormality of each organ until now, technology to be evaluated as an organ that is connected by a network was missing. In addition, a technique for evaluating the reactions that occur in the long term have been developed, but the technology to evaluate the reactions that occur in all time scales, including a short period of time was missing. By using to develop a system that can be measured the cellular quality of bioactivities in real-time, make the establishment of technology to evaluate the reactions in all time scales and the whole body in this study.
Publication
- Nimura, K., Yamamoto, M., Takeichi, M., Saga, K., Takaoka, K., Kawamura, N., Nitta, H., Nagano, H., Ishino, S., Tanaka, T., Shwartz, R.J., Aburatani, H., Kaneda, Y. Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development. ELife, 2016, 5: e16030
- Nakano, M., Imamura, H., Sasaoka, N., Yamamoto, M., Uemura, N., Shudo, T., Fuchigami, T., Takahashi, R. and Kakizuka, A. ATP Maintenance via Two Types of ATP Regulators Mitigates Pathological Phenotypes in Mouse Models of Parkinson’s Disease. EBioMedicine, 2017, 22: 225-241