Identification and analysis of small proteins coded by long non-coding RNAs
Akinobu Matsumoto
| Research Site | Kyushu University |
|---|---|
| Medical Institute of Bioregulation | |
| Associate Professor |
Content
Transcriptome analysis reveals a number of long non-coding RNAs (lncRNAs) that do not appear to harbor significant open reading frames. However, I have identified a lot of small proteins coded by lncRNAs and analyzing their molecular and biological importance. My goal is to uncover new insights into the cause of diseases by analyzing new factors, small proteins.
Publication
- Matsumoto A., Pasut A., Matsumoto M., Yamashita R., Fung J., Monteleone E. Saghatelian A., Nakayama KI., Clohessy JG, Pandolfi PP.: mTORC1 and muscle regeneration are regulated by the LINC00961 encoded SPAR polypeptide. Nature, 12;541(7636):228-232 (2017).
