科学技術振興機構 さきがけ エピジェネティクスの制御と生命機能 エピジェネティクスの制御と生命機能さきがけ独立行政法人科学技術振興機構

研究成果

有吉 眞理子 (Mariko Ariyoshi)

論文

  1. Junji Otani 1, Kyohei Arita 1, Tsuyoshi Kato 1, Mariko Kinoshita 1, Hironobu Kimura 2, Isao Suetake 2, Shoji Tajima 2, Mariko Ariyoshi 3,4* and Masahiro Shirakawa 1,5,6*,:Structural basis of the versatile DNA recognition ability of the methyl CpG binding domain of methyl-CpG binding domain protein 4,The Journal of Biological Chemistry doi/10,1074/jbc

  2. Otani J., Nankumo T., Arita K., *Inamoto S., *Ariyoshi M. and *Shirakawa M. :Structural basis for recognition of H3K4 methylation status by the DNMT3A ADD domain. EMBO report. 10:1235-1241, 2009
  3. Sekiyama N., Arita K., Ikeda Y., *Ariyoshi M., Tochio H., Saitoh H. and *Shirakawa M.: SUMOylation regulated by SUMO-like domain in Nip45. Proteins in press.
  4. Isogai S., Kanno S., Ariyoshi M., *Toshio H., Ito Y., Yasui A. and *Shirakawa M: Solution structure of a zinc-finger domain that binds to poly-ADP-ribose. Genes to Cells in press.
  5. Tateishi Y, *Ariyoshi M, Igarashi R, Hara H, Mizuguchi K, Seto A, Nakai A, Kokubo T, Tochio H, *Shirakawa M. Molecular basis for SUMOylation-dependent regulation of DNA binding activity of heat shock factor 2. J Biol Chem. 23;284:2435-47, 2009
  6. Arita K, *Ariyoshi M, Tochio H, Nakamura Y, *Shirakawa M. Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature. 455: 818-21, 2008
  7. Sekiyama N, Ikegami T, Yamane T, Ikeguchi M, Uchimura Y, Baba D, Ariyoshi M, Tochio H, Saitoh H, *Shirakawa M. Structure of the small ubiquitin-like modifier (SUMO)-interacting motif of MBD1-containing chromatin-associated factor 1 bound to SUMO-3. J Biol Chem. 283:35966-75. 2008
  8. Yamada K, Ariyoshi M, *Morikawa K. Three-dimensional structural views of branch migration and resolution in DNA homologous recombination. Curr Opin Struct Biol. 14:130-7, 2004
  9. Ariyoshi M, *Schwabe JW. A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling. Genes Dev. 17: 1909-20. 2003
  10. Yamada K, Miyata T, Tsuchiya D, Oyama T, Fujiwara Y, Ohnishi T, Iwasaki H, Shinagawa H, Ariyoshi M, Mayanagi K, *Morikawa K. Crystal structure of the RuvA-RuvB complex: a structural basis for the Holliday junction migrating motor machinery. Mol Cell. 10:671-81, 2002.
  11. Yamamoto-Katayama S, Ariyoshi M, Ishihara K, Hirano T, Jingami H, *Morikawa K. Crystallographic studies on human BST-1/CD157 with ADP-ribosyl cyclase and NAD glycohydrolase activities. J Mol Biol. 316:711-23, 2002
  12. Ariyoshi M, Nishino T, Iwasaki H, Shinagawa H, *Morikawa K. Crystal structure of the holliday junction DNA in complex with a single RuvA tetramer. Proc Natl Acad Sci U S A. 97:8257-62, 2000

総説

  1. 新生DNA鎖へのメチル化パターン継承のメカニズム 有吉眞理子、有田恭平、白川昌宏
    Medical Bio 38巻 72-78, 2008