資料1

戦略的創造研究推進事業 総括実施型研究(ICORPタイプ)
(平成16年度発足)


<研究領域>
「膜機構」

<研究総括>
楠見 明弘 氏
(京都大学 再生医科学研究所 教授)

相手側研究総括の略歴等
(相手国:インド)

Name
Satyajit Mayor

Address
National Centre for Biological Sciences
UAS-GKVK Campus Bellary Road. Bangalore 560065 India

University Education
Ph.D. Rockefeller University, NY, USA.  1991  Life Science
M.Sc. I IT, Bombay,India           1985  Chemistry

Details of Employment
- Associate Professor: February 2001 - present.
- Reader (SE) [Assistant Professor]: September 1995 - February 2001:
- National Centre for Biological Sciences, Bangalore.
- Lecturer, Woodshole Microscopy Course, Woodshole, Massachusetts, USA, October 1994.

Professional Recognition, Awards and Scholarships
- Fellow, Indian National Science Academy, 2004
- Shanti Swaroop Bhatnagar Award, 2003
- Swarnajayanti Fellowship, Department of Science and Technology, 2003-2008
- Fellow, Indian Academy of Sciences, 2001.
- Mizutani Foundation: Grant for Glycosciences research, April 2001-March 2002
- Wellcome Trust International Senior Research Fellow (Biomedical Research, India), 1999-2004
- Associate of the Third World Academy of Sciences, Trieste, 1998
- Member, International Affairs Committee, American Society for Cell Biology (1997-2002)
- Recipient of Human Frontier Science Program Research Grant (1996)
- Helen Hays Whitney Post-Doctoral Fellowship (1992-1995)
- The Rockefeller-Oxford Student Exchange Program Recipient (1988)
- Lucille P. Markey Charitable Trust Graduate Fellowship (1986-1991)
- Visiting Students Research Program Recipient (TIFR) (1984)

Research Experience
- Associate Professor. Feb 2000- till present
- Reader Sept 1995-2000.
National Centre for Biological Sciences, TIFR Centre, Bangalore, India.
General Research Area: Molecular mechanisms in endocytosis in metazoan cells.
- Post-Doctoral Training: May 1991- 1995;
Department of Pathology, Columbia University College of Physicians and Surgeons, New York, NY. Topic: Endocytic traffic of membrane lipids and GPI-anchored proteins In the laboratory of Dr. Frederick. R. Maxfield (Dept. Pathology, Columbia University)
- Ph.D. Thesis, 1991, Rockefeller University, USA
- The Rockefeller-Oxford Student Exchange Program. Summer 1988
- FEBS Practical/Lecture Course on Intracellular Protein Transport, June, 1987.
- M.Sc. Thesis, 1985, IIT Bombay, India
- Visiting Students Research Program May-July 1984

Selected Publications
  1. Sharma, P., Varma, R., Sarasij, R. C., Ira, Gousset, K., Krishnamoorthy, G., Rao, M., and Mayor, S. Nanoscale organization of multiple GPI-anchored proteins in living cell membranes. Cell 116, 577-589 (2004).
  2. Sriram, V, Krishnan, K. S., & Mayor, S. deep-orange and carnation define distinct stages in late endosomal biogenesis in Drosophila melanogaster. J. Cell Biol. 161, 593-607 (2003).
  3. Sabharanjak, S., Sharma, P., Parton, R. G. & Mayor, S. GPI-anchored proteins are delivered to recycling endosomes via a distinct cdc42-regulated, clathrin-independent pinocytic pathway. Dev. Cell 2, 411-23 (2002).
  4. Chatterjee, S., Smith, E. R., Hanada, K., Stevens, V. L. & Mayor, S. GPI anchoring leads to sphingolipid-dependent retention of endocytosed proteins in the recycling endosomal compartment. EMBO J. 20, 1583-1592 (2001).
  5. Varma, R. & Mayor, S. GPI-anchored proteins are organized in sub-micron sized domains at the cell surface. Nature 394, 798-810 (1998).
  6. Mayor, S., Sabharanjak, S. & Maxfield, F.R. Cholesterol regulates the retention of GPI-anchored proteins in endosomes. EMBO J. 17, 4626-4638 (1998).
  7. Mayor, S., Rothberg, K.G. & Maxfield, F.R. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 264, 1948-51 (1994).
  8. Mayor, S., Presley, J.P. & Maxfield, F.R. Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process. J. Cell Biol. 121, 1257-1269 (1993).
  9. Mayor, S., Menon, A. K. & Cross, G. A. M. Transfer of glycosyl-phosphatidylinositol membrane anchors to protein in a cell free system. J. Cell Biol. 114, 61-71 (1991).
  10. Mayor, S, and Rao, M. Rafts: Scale dependent active lipid dependent organization at the cell surface. Traffic 5, 231-240 (2004).
  11. Mayor, S., and Riezman, H. Sorting GPI-anchored proteins. Nature Reviews Molecular Cell Biology 5, 110-132 (2004).