Home > Press Releases > Press Release #1202 > Appendix 1
Appendix 1

Japan-France Collaborative Research Projects

Project Title Japanese Researcher Position and Institution Abstract of Research Project
French Researcher
1 “Molecular Memory with Phase Change Coordination Polymers for future PCRAM” Satoshi HORIKE Assistant Professor, Graduate School of Engineering, Kyoto University This research project aims to develop a new class of memory materials for future electronic technology by use of molecules. Japanese team is responsible for control of switching behavior of the molecular memory and the fabrication of the materials as device platform. French team is responsible for synthesis of molecular memory materials. The bilateral collaboration provides the conceptual molecular memory materials showing “low energy consumption”“small size and high memory density”, and “flexibility for wearable devices”.
Aude DEMESSENCE Researcher, Sustainable chemistry team, Institute of Researches on Catalysis and Environment at Lyon
2 “Intracellular tracking of protein function by design and synthesis of fluorogenic probes for MEMORY imaging” Kazuya KIKUCHI Professor, Graduate School of Engineering, Osaka University GLUT4 is an N-glycosylated protein that regulates glucose homeostasis by the intracellular trafficking of the protein and is involved with type II diabetes. To date, it has been elusive whether the N-glycan of GLUT4 contributes to the intracellular trafficking. To clarify the physiological role of the N-glycan, we applied PYP (Photoactive yellow protein)-tag technology for the imaging analyses of GLUT4 trafficking. PYP-tag ligands are developed as fluorogenic probes that bind to PYP-tag and enhance fluorescence intensity upon the labeling reactions. By using the fluorogenic probes, we clarified the function of the N-glycan in the intracellular trafficking of GLUT4 and the localization “log” has been imaged. By the collaboration with French group’s technique, we will materialize the robustness of our molecular technology for MEMORY imaging.
Jens HASSERODT Professor of Chemistry, Ecole Normale Supérieure de Lyon
3 “On-surface synthesis of covalent networks with integrated optical functions” Yousoo KIM Chief Scientist,
Surface and Interface Science Laboratory, RIKEN
The present PHOTONET project aims at developing an adaptive 2D covalent network as a universal scheme for creating robust organic surfaces with designed optical properties, providing a platform for the next-generation of molecular-based devices. To this aim, a surface-supported extended covalent network will be formed through in-situ reaction from functionalized precursor molecules. The strategy proposed enables incorporation of targeted molecular functions into large scale, extended regular networks while preserving their original molecular-level physicochemical properties on metal or insulating substrates. The consortium of the project is composed of three research laboratories. French partners will create 2D covalent networks on solid surfaces (IM2NP) and develop new methodologies in organic synthesis of molecular precursors (ISM2). Japan partner will investigate molecular functions with low-temperature scanning probe microscopy and theoretical calculations (RIKEN). The 2D covalent networks realized by the PHOTNET project will provide an efficient and multifunctional platform for the next-generation of molecular-based devices.
Sylvain CLAIR CNRS Senior Researcher,
IM2NP (Institut Matériaux Microélectronique Nanosciences de Provence)
4 “Versatile ultra-sensitive FET sensor: Application to the detection of Cesium in natural waters” Yutaka
Group Leader, International Center for Materials Nanoarchitectonics,
National Institute for Materials Science
The first target of this project is to develop an OFET-based sensor to detect radioactive Cs+ ions with ultra-high sensitivity and selectivity. To realize this purpose, an interdisciplinary consortium is organized from the research fields of fundamental materials science and applicative device engineering. France team is mainly in charge of molecular synthesis of calixarenes for chelating Cs+ ions and lipid membranes for grafting ion recognizing calixarenes. Meanwhile, Japan team is responsible to grow the organic semiconducting channel layer and to assemble the respective components into OFET device configuration. Both of the teams will examine ion-sensing properties and feedback the information for further optimization of the molecular and device structures, respectively. Once the device mechanism is established, our proposed ion-sensor can be generalized to a versatile ion sensor just by changing ion chelating parts.
Anne CHARRIER CNRS researcher, CINaM
(Centre Interdisciplinaire de Nanoscience de Marseille)

JST, an integrated organization of science and technology in Japan, establishes an infrastructure for the entire process from the creation of knowledge to the return to the society. For more information, visit http://www.jst.go.jp/EN/