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Attachment 1

"FY2013 Strategic International Research Cooperative Program (SICP)"
Japan-Brazil Research Exchange Projects

Project Title Japanese
Position and Institution Abstract of Research Project
1 Bio-functionalization of Ti-based materials for osseointegrated implants Takao Hanawa Professor,
Institute of Biomaterials and Bioegineering, Tokyo Medical and Dental University
The main aim of this project is to develop a new generation of bio-multifunctional Ti-based surfaces for osseointegrated implants. In particular the goal is to play with different surface modification techniques to obtain surfaces capable of being biologically selective, together with high corrosion and tribocorrosion resistance. Japanese-side conducts development of surface modification techniques and evaluation of surface modified materials; Brazilian-side conducts evaluation of tribo-corrosion and adhesion of cells and bacteria. The multi-disciplinary team integrating this project will become available for the future production of improved implant multifunctional surfaces and promote expertise of the Brazilian and Japanese teams throughout the project.
Luís Augusto Sousa Marques da Rocha Prof. Ass. Doutor,
Departamento de Fisica, Faculdade de Ciencias de Bauru, Universidade Estadual Paulista
2 Amazon fruits nano-supplements development: nutrigenomic and nutrigenetic effects on aging and health (EPIDIET PROJECT) Toshiro Aigaki Professor,
the Graduate School of Science and Engineering, Tokyo Metropolitan University
This project aims at developing nano-supplements promoting human health and longevity, through elucidating the functionality of Amazonian fruits at molecular, cellular and organismal levels using in vitro and in vivo experimental systems. Specifically, the Japanese researchers will be in charge of investigating the effects of Amazonian fruit extracts or nano-supplements using Drosophila melanogaster an in vivo model, and the Brazilian researchers will perform in vitro experiments and clinical studies in humans. By working together, it is expected that the mechanisms underlying the functionality of Amazonian fruits will be revealed, and effective and safe nano-supplements promoting human health and longevity will be developed.
Ivana Beatrice Manica Da Cruz Professor,
Centro de Ciencias da Saude/Departamento de Morfologia, Universidade Federal de Santa Maria
3 Evaluation of different extracts and isolated compounds from Brazilian Propolis in obesity and diabetes via in vitro and in vivo assay Je Tae Woo Professor,
Department of Biological Chemistry, College of Bioscience and Biotechnology, Chubu University
Propolis is a natural resin with antibiotic effects which honey bees collect from botanical sources, and it has been used as health foods. This project aims to obtain scientific evidences for the development of nano-functional foods of for prevention and improvement of obesity and diabetes with the use of Brazilian green propolis. Brazilian groups will isolate various functional components of the Brazilian green propolis and prepare their nano-particulate composite with chitosan. Japanese groups will investigate their effects on cellular and animal model of obesity and diabetes. By working together, it is expected to obtain scientific evidences for the use of Brazilian green propolis into functional foods for the prevention and improvement of obesity and diabetes and to strengthen research networks between Japan and Brazil.
Jairo Kenupp Bastos Professor,
School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo

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