They found that a cobalt catalyst promotes dehydrative direct functionalization of carbon-hydrogen bond in organic molecules with allylic alcohols, leading to short, low-costing, and environmentally-friendly synthesis of medicines.
JST ACT-C (Advanced Catalytic Transformation Program for Carbon Utilization)
Research Area “Creation of Advanced Catalytic Transformation for the Sustainable Manufacturing at Low Energy, Low Environmental Load”
Research Theme “Development and Applications of Cooperative Catalysts towards Life Innovation”
Yudai Suzuki, Bo Sun, Ken Sakata, Tatsuhiko Yoshino, Shigeki Matsunaga, and Motomu Kanai. “Dehydrative Direct C-H Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis”. Angewadnte Chemie International Edition, 2015, Early View, doi: 10.1002/anie.201503704.
Shigeki Matsunaga Ph.D.
Professor, Laboratory of Synthetic and Industrial Chemistry, Faculty of Pharmaceutical Sciences, Hokkaido University
Department of Research Project, JST