They found that a cobalt(III) catalyst in combination with an acetate ion works cooperatively and shows wider applicability than conventional rhodium(III) catalysts. This result is expected, and greatly contributes to an efficient, low-costing, and environmentally-friendly synthesis of medicines.
Researcher Information
JST ACT-C (Advanced Catalytic Transformation Program for Carbon Utilization),
Research Area: “Creation of Advanced Catalytic Transformation for the Sustainable Manufacturing at Low Energy, Low Environmental Load”,
Research Theme: Development and Applications of Cooperative Catalysts towards Life Innovation
Journal Information
Hideya Ikemoto, Tatsuhiko Yoshino, Ken Sakata, Shigeki Matsunaga, and Motomu Kanai,
“Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C-H Alkenylation/Annulation Sequence”
Journal of the American Chemical Society, 2014, in press.
doi: 10.1021/ja5008432
Contact
[About Research]
Shigeki Matsunaga Ph.D.
Associate Professor
Laboratory Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences,
The University of Tokyo
E-mail: 
http://www.f.u-tokyo.ac.jp/~kanai/e_index.html
[About Program]
Tsuyoshi Nakamura
Department of Research Project
Japan Science and Technology Agency (JST)
E-mail: 