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JST Press Release

Oct.3, 2012

Japan Science and Technology Agency (JST)
5-3, Yonbancho, Chiyoda-ku, Tokyo 102-8666

Success in taking a protein alive in an artificial capsule

The synthesis of the precise artificial capsules which can encapsulate huge molecules like a protein was first achieved utilizing self-assembly process, where metal ions and organic compounds are just mixed in a flask. A wide variety of applications in the fields of industry, drug discovery, and so on are expected, because the encapsulation of proteins could be useful for structural analysis or functional improvement of the trapped proteins.


Researcher Information

JST CREST Research Area “Development of the foundation for nano-interface technology”,
Research Theme: “Self-assembled Discrete Nanointerfaces”

Journal Information

Published in “Nature Communications”, scientific journal of Nature Publishing Group

Daishi Fujita, Kosuke Suzuki, Sota Sato, Maho Yagi-Utsumi, Yoshiki Yamaguchi, Nobuhiro Mizuno, Takashi Kumasaka, Masaki Takata, Masanori Noda, Susumu Uchiyama, Koichi Kato and Makoto Fujita. “Protein encapsulation within synthetic molecular hosts” Nature Commun., 2012

doi: 10.1038/ncomms2093


[About Research]
Makoto Fujita Ph.D.,
Professor, Department of Applied Chemistry, School of Engineering,
The University of Tokyo

Koichi Kato Ph.D.,
Professor, Department of Life and Coordination-Complex Molecular Science, Institute for Molecular Science and Department of Bioenvironmental Science, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences

[About Program]

Green Innovation Group, Department of Innovation Research, Japan Science and Technology Agency, Masashi Furukawa,


JST, an integrated organization of science and technology in Japan, establishes an infrastructure for the entire process from the creation of knowledge to the return to the society. For more information, visit http://www.jst.go.jp/EN/