Single-molecule digital ELISA (Enzyme-Linked Immunosorbent Assay) has realized millionfold improvement of the detection limit of a biomarker for prostate cancer. In the near future, this method will lead to a highly-sensitive portable device for the earliest diagnosis of many diseases and infections.
JST CREST Research Area "Creation of Nanosystems with Novel Functions through Process Integration", Research Theme : "Digital counting systems for biological assay"
Published in "Lab on a chip", scientific journal of Royal Society of Chemistry
Soo Hyeon Kim, Shino Iwai, Suguru Araki, Shouichi Sakakihara, Ryota Iino and Hiroyuki Noji. "
Large-scale femtoliter droplet array for digital counting of single biomolecules"
Lab on a chip, 2012
Link to the article: http://pubs.rsc.org/en/content/articlelanding/2012/LC/C2LC40632B
About Research :
Ryota IINO Ph.D.
Lecturer, Department of Applied Chemistry, School of Engineering, The University of Tokyo
About Program :
Green Innovation Group, Department of Innovation Research,
Japan Science and Technology Agency,