[Takayuki Yamashita] Development of non-invasive optical intervention techniques for elucidation of neural basis of animal behavior

Research Director

Takayuki Yamashita

Takayuki Yamashita

Research Institute of Environmental Medicine, Nagoya University
Assistant Professor
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Outline

Optogenetics is a revolutionary technique that makes it possible to manipulate specific neuronal activities with light and to interrogate their function in ongoing animal behavior. However, with optogenetics of the current status, it is impossible to freely operate cellular function deep in the tissue without invasiveness through insertion of an optic fiber. Using nano-materials that receive electromagnetic waves to emit visible light, I here attempt to develop novel, minimally-invasive techniques that enable one to activate or inactivate neurons deep in the tissue, in a large volume and with a high temporal resolution.

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