[Satoshi Yamaguchi] Photo-responsive cell-immobilization surfaces for single-cell manipulation

Research Director

Satoshi Yamaguchi

Satoshi Yamaguchi

Research Center for Advanced Science and Technology, The University of Tokyo
Lecturer
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Outline

In this project, we develop single-cell manipulation surfaces on which cells are rapidly adhered or released on/from desired positions at a single-cell level. On the surfaces coated with photo-responsive materials, multiple cells can be freely patterned and arrayed in a light-guided manner, and accordingly, the properties and interactions of individual cells are accurately investigated in a high-throughput manner. Furthermore, only the desired cells are selectively obtained by light irradiation. This technology is expected to be applied to isolation of cancer cells from blood samples for assessment of cancer therapy and purification of functional cells for cell therapy and tissue engineering.

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