[Ryuji Igarashi] Development of nanodiamond bioimaging for three-dimensional structural dynamics

Presto Researcher

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Ryuji Igarashi

Japan Science and Technology Agency
PRESTO Researcher

Outline

In order to understand the functions and characteristics of individual cells, it is essential to three-dimensionally visualize structural changes of intracellular biomolecules responsible for various biological activities. In this study, I will establish a fundamental bioimaging techniqe to visualize the 3D dynamics of intracellular biomolecules based on our previously developed “optically-detected magnetic resonance microscope” and molecular targeting approachs utilizing fluorescent nanodiamonds. Our bioimaging technique could be a breakthrough to uncover how mechanical/thermal signal is sensed by cells and transduced into cellular signaling pathways.

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