[Hiroto Katoh] High-throughput Functional Genomics Screenings to Discover Novel Anti-Cancer Metabolomics Targets by Combining Human shRNA and Microbial cDNA Libraries.

PRESTO Researcher

Hiroto Katoh

Hiroto Katoh

Department of Genomic Pathology, Medical Research Institute, Tokyo Medical and Dental University
Assistant Professor

Outline

Cancer is a metabolic disease and often exhibits durable dependencies onto specific metabolic activities of the malignant cells for its growth. By targeting such metabolic Achilles heels of cancer cells, one can establish efficient therapeutic strategies against malignancies. By conducting high-throughput functional genomics screenings using both human shRNA and microbial cDNA libraries, I will search for novel anti-cancer molecules with a special focus on metabolism-related targets.

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