[Takahiro Shibata] Establishment of analytical method of protein adductome

PRESTO Researcher

Takahiro Shibata

Takahiro Shibata

Graduate School of Bioagricultural Sciences, Nagoya University
Associate Professor

Research Outline

The oxidized fatty acids generated during oxidative stress or inflammatory conditions can react with proteins and form various adducts. These post-translational modifications of protein may serve as a good indicator of disease-associated conditions. In this study, we attempt to develop an analytic method for “the protein adductome”, representing the totality of covalent adducts bound to proteins. Such analytic method may be useful for various medical applications.

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